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Tmem102 Gene Detail
Summary
  • Symbol
    Tmem102
  • Name
    transmembrane protein 102
  • Synonyms
    Cbap, Tmem102-ps
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921591
    NCBI Gene: 380705
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:69694429-69696450 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 42.88 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    85 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921591
 protein coding gene Chr11:69694421-69696450 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018556
 protein coding gene Chr11:70283424-70285446 (-)
A/J MGP_AJ_G0018524
 protein coding gene Chr11:67624544-67626565 (-)
AKR/J MGP_AKRJ_G0018493
 protein coding gene Chr11:69643818-69645840 (-)
BALB/cJ MGP_BALBcJ_G0018496
 protein coding gene Chr11:67951916-67953937 (-)
C3H/HeJ MGP_C3HHeJ_G0018309
 protein coding gene Chr11:69675542-69677563 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018947
 protein coding gene Chr11:72405639-72407660 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016592
 protein coding gene Chr11:64546626-64548649 (-)
CAST/EiJ MGP_CASTEiJ_G0017864
 protein coding gene Chr11:69913470-69915490 (-)
CBA/J MGP_CBAJ_G0018282
 protein coding gene Chr11:75649132-75651153 (-)
DBA/2J MGP_DBA2J_G0018391
 protein coding gene Chr11:67207230-67209249 (-)
FVB/NJ MGP_FVBNJ_G0018381
 protein coding gene Chr11:66848322-66850343 (-)
LP/J MGP_LPJ_G0018461
 protein coding gene Chr11:70848169-70850191 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018404
 protein coding gene Chr11:76256405-76258426 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018989
 protein coding gene Chr11:69906305-69908326 (-)
PWK/PhJ MGP_PWKPhJ_G0017638
 protein coding gene Chr11:67857637-67859657 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017428
 protein coding gene Chr11:69727218-69729235 (-)
WSB/EiJ MGP_WSBEiJ_G0017918
 protein coding gene Chr11:69574212-69576235 (-)



Homology
more
  • Human Ortholog
    TMEM102, transmembrane protein 102
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM102, transmembrane protein 102
  • Synonyms
    CBAP, D2B
  • Links
    NCBI Gene ID: 284114
    neXtProt AC: NX_Q8N9M5
    UniProt: Q8N9M5

  • Chr Location
    17p13.1; chr17:7435435-7437679 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous KO affects chemotaxis in primary T cells.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    6
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000089876 Ensembl Gene Model | MGI Sequence Detail 2022 C57BL/6J ±  kb
transcript ENSMUST00000051025 Ensembl | MGI Sequence Detail 1933 Not Applicable  
polypeptide ENSMUSP00000132164 Ensembl | MGI Sequence Detail 509 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 1
References
more
  • Summaries
    All 31
    Gene Ontology 6
    Phenotypes 11
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:200103 Chiang YJ, et al., CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-Cell adhesion and migration. PLoS One. 2013;8(4):e61761
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory