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Parpbp Gene Detail
Summary
  • Symbol
    Parpbp
  • Name
    PARP1 binding protein
  • Synonyms
    4930547N16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922567
    NCBI Gene: 75317
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:87927294-87982803 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 43.70 cM, cytoband C2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1211 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922567
 protein coding gene Chr10:87927260-87982831 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017622
 protein coding gene Chr10:89160303-89214960 (-)
A/J MGP_AJ_G0017601
 protein coding gene Chr10:86159420-86207150 (-)
AKR/J MGP_AKRJ_G0017559
 protein coding gene Chr10:88604900-88657441 (-)
BALB/cJ MGP_BALBcJ_G0017564
 protein coding gene Chr10:86437279-86486873 (-)
C3H/HeJ MGP_C3HHeJ_G0017387
 protein coding gene Chr10:88588440-88637060 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018021
 protein coding gene Chr10:92153612-92211132 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015703
 protein coding gene Chr10:81921947-81968673 (-)
CAST/EiJ MGP_CASTEiJ_G0016952
 protein coding gene Chr10:88485530-88539960 (-)
CBA/J MGP_CBAJ_G0017356
 protein coding gene Chr10:95975419-96034818 (-)
DBA/2J MGP_DBA2J_G0017462
 protein coding gene Chr10:85277651-85325135 (-)
FVB/NJ MGP_FVBNJ_G0017454
 protein coding gene Chr10:84505011-84552613 (-)
LP/J MGP_LPJ_G0017536
 protein coding gene Chr10:89837613-89890673 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017485
 protein coding gene Chr10:97491478-97546274 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018058
 protein coding gene Chr10:88440918-88488461 (-)
PWK/PhJ MGP_PWKPhJ_G0016733
 protein coding gene Chr10:85284965-85333832 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016520
 protein coding gene Chr10:87172487-87221716 (-)
WSB/EiJ MGP_WSBEiJ_G0017011
 protein coding gene Chr10:88399795-88459595 (-)



Homology
more
  • Human Ortholog
    PARPBP, PARP1 binding protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PARPBP, PARP1 binding protein
  • Synonyms
    AROM, C12orf48, PARI
  • Links
    NCBI Gene ID: 55010
    neXtProt AC: NX_Q9NWS1
    UniProt: Q9NWS1

  • Chr Location
    12q23.2; chr12:102120183-102197520 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotype references
  • All Mutations and Alleles
    14
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    3
  • Targeted
    8
  • Genomic Mutations
    1 involving Parpbp
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    35 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    739
  • Tissues
    26
  • cDNA Data
    26
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000035365 Ensembl Gene Model | MGI Sequence Detail 55510 C57BL/6J ±  kb
transcript ENSMUST00000048518 Ensembl | MGI Sequence Detail 3594 Not Applicable  
polypeptide ENSMUSP00000038375 Ensembl | MGI Sequence Detail 573 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 27
    cDNA 27

    Microarray probesets 4
Other
Accession IDs
less
MGI:2143631
References
more
  • Summaries
    All 49
    Developmental Gene Expression 5
    Gene Ontology 5
    Phenotypes 16
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory