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Atf7ip2 Gene Detail
Summary
  • Symbol
    Atf7ip2
  • Name
    activating transcription factor 7 interacting protein 2
  • Synonyms
    4930558K11Rik, Get-1, MGC:6783, PSM2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922579
    NCBI Gene: 75329
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:10010513-10068595 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 16, 5.50 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1171 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922579
protein coding gene Chr16:10010513-10069342 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022503
protein coding gene Chr16:6965946-7020462 (+)
A/J MGP_AJ_G0022465
protein coding gene Chr16:6592961-6640075 (+)
AKR/J MGP_AKRJ_G0022441
protein coding gene Chr16:6914377-6962229 (+)
BALB/cJ MGP_BALBcJ_G0022469
protein coding gene Chr16:6729488-6777763 (+)
C3H/HeJ MGP_C3HHeJ_G0022236
protein coding gene Chr16:6944995-6995089 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022918
protein coding gene Chr16:7122144-7174000 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020439
protein coding gene Chr16:6730100-6785422 (+)
CAST/EiJ MGP_CASTEiJ_G0021763
protein coding gene Chr16:6977766-7036532 (+)
CBA/J MGP_CBAJ_G0022205
protein coding gene Chr16:7405575-7465933 (+)
DBA/2J MGP_DBA2J_G0022336
protein coding gene Chr16:6598613-6649454 (+)
FVB/NJ MGP_FVBNJ_G0022312
protein coding gene Chr16:6588104-6638639 (+)
LP/J MGP_LPJ_G0022404
protein coding gene Chr16:6932570-6985958 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022334
protein coding gene Chr16:7148374-7199247 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022931
protein coding gene Chr16:6848535-6897270 (+)
PWK/PhJ MGP_PWKPhJ_G0021503
protein coding gene Chr16:6799222-6847849 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021333
protein coding gene Chr16:6913869-6964511 (+)
WSB/EiJ MGP_WSBEiJ_G0021811
protein coding gene Chr16:6914682-6964451 (+)



Homology
more
  • Human Ortholog
    ATF7IP2, activating transcription factor 7 interacting protein 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ATF7IP2, activating transcription factor 7 interacting protein 2
  • Synonyms
    MCAF2
  • Links
    NCBI Gene ID: 80063
    neXtProt AC: NX_Q5U623
    UniProt: Q5U623

  • Chr Location
    16p13.2-p13.13; chr16:10326434-10483638 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 75329 NCBI Gene Model | MGI Sequence Detail 58083 C57BL/6J ±  kb
transcript NM_153123 RefSeq | MGI Sequence Detail 2584 C57BL/6  
polypeptide Q3UL97 UniProt | EBI | MGI Sequence Detail 452 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000004406 activating transcription factor 7-interacting protein 2
  • InterPro Domains
    IPR026085 Activating transcription factor 7-interacting protein
    IPR031870 ATF7-interacting protein , protein binding domain
    IPR003961 Fibronectin type III
    IPR036116 Fibronectin type III superfamily
    IPR013783 Immunoglobulin-like fold
Molecular
Reagents
less
  • All nucleic 21
    cDNA 17
    Primer pair 2
    Other 2

    Microarray probesets 6
Other
Accession IDs
less
MGI:2385609
References
more
  • Summaries
    All 34
    Developmental Gene Expression 4
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:343163 Shao Q, et al., ATF7IP2, a meiosis-specific partner of SETDB1, is required for proper chromosome remodeling and crossover formation during spermatogenesis. Cell Rep. 2023 Aug 4;42(8):112953

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory