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Arhgap36 Gene Detail
Summary
  • Symbol
    Arhgap36
  • Name
    Rho GTPase activating protein 36
  • Synonyms
    1100001E04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922654
    NCBI Gene: 75404
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:48552822-48589121 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 25.95 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    512 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922654
 protein coding gene ChrX:48537237-48589121 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035701
 protein coding gene ChrX:44635651-44672653 (+)
A/J MGP_AJ_G0035684
 protein coding gene ChrX:44458118-44494330 (+)
AKR/J MGP_AKRJ_G0035604
 protein coding gene ChrX:45708797-45748555 (+)
BALB/cJ MGP_BALBcJ_G0035670
 protein coding gene ChrX:44093631-44129753 (+)
C3H/HeJ MGP_C3HHeJ_G0035374
 protein coding gene ChrX:44913082-44949356 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036199
 protein coding gene ChrX:45662290-45698557 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033051
 protein coding gene ChrX:42119440-42155516 (+)
CAST/EiJ MGP_CASTEiJ_G0034665
 protein coding gene ChrX:32458053-32498762 (+)
CBA/J MGP_CBAJ_G0035348
 protein coding gene ChrX:46982208-47018551 (+)
DBA/2J MGP_DBA2J_G0035502
 protein coding gene ChrX:44317976-44356323 (+)
FVB/NJ MGP_FVBNJ_G0035451
 protein coding gene ChrX:44030201-44066372 (+)
LP/J MGP_LPJ_G0035590
 protein coding gene ChrX:44993311-45029568 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035489
 protein coding gene ChrX:48417689-48454542 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036217
 protein coding gene ChrX:44529283-44571031 (+)
PWK/PhJ MGP_PWKPhJ_G0034364
 protein coding gene ChrX:31922226-31958816 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034209
 protein coding gene ChrX:33278123-33321779 (+)
WSB/EiJ MGP_WSBEiJ_G0034809
 protein coding gene ChrX:44134028-44171301 (+)



Homology
more
  • Human Ortholog
    ARHGAP36, Rho GTPase activating protein 36
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ARHGAP36, Rho GTPase activating protein 36
  • Links
    NCBI Gene ID: 158763
    neXtProt AC: NX_Q6ZRI8
    UniProt: Q6ZRI8

  • Chr Location
    Xq26.1; chrX:131058346-131089885 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Inactivation of this gene results in specific reduction of lateral motor column motor neurons in the developing embryonic spinal cord.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    836
  • Tissues
    11
  • cDNA Data
    4
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036198 Ensembl Gene Model | MGI Sequence Detail 36300 C57BL/6J ±  kb
transcript ENSMUST00000114904 Ensembl | MGI Sequence Detail 3033 Not Applicable  
polypeptide ENSMUSP00000110554 Ensembl | MGI Sequence Detail 590 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 5
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 28
    Developmental Gene Expression 4
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory