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Rilpl1 Gene Detail
Summary
  • Symbol
    Rilpl1
  • Name
    Rab interacting lysosomal protein-like 1
  • Synonyms
    2900002H16Rik, 6330559I19Rik, GOSPEL
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922945
    NCBI Gene: 75695
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:124631143-124669454 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 63.62 cM, cytoband F
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1127 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922945
 protein coding gene Chr5:124631143-124669684 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030098
 protein coding gene Chr5:128323039-128361420 (-)
A/J MGP_AJ_G0030063
 protein coding gene Chr5:122967164-123005518 (-)
AKR/J MGP_AKRJ_G0029999
 protein coding gene Chr5:126936833-126974912 (-)
BALB/cJ MGP_BALBcJ_G0030074
 protein coding gene Chr5:124306486-124344935 (-)
C3H/HeJ MGP_C3HHeJ_G0029791
 protein coding gene Chr5:127547340-127586428 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030527
 protein coding gene Chr5:133289641-133340036 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027753
 protein coding gene Chr5:117493382-117533838 (-)
CAST/EiJ MGP_CASTEiJ_G0029199
 protein coding gene Chr5:126645166-126698110 (-)
CBA/J MGP_CBAJ_G0029761
 protein coding gene Chr5:138521409-138562049 (-)
DBA/2J MGP_DBA2J_G0029911
 protein coding gene Chr5:122988092-123026785 (-)
FVB/NJ MGP_FVBNJ_G0029867
 protein coding gene Chr5:122031931-122073223 (-)
LP/J MGP_LPJ_G0030000
 protein coding gene Chr5:128856532-128894072 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029898
 protein coding gene Chr5:142087021-142126136 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030568
 protein coding gene Chr5:126558090-126596393 (-)
PWK/PhJ MGP_PWKPhJ_G0028913
 protein coding gene Chr5:121800363-121851787 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028750
 protein coding gene Chr5:124165750-124217116 (-)
WSB/EiJ MGP_WSBEiJ_G0029274
 protein coding gene Chr5:127242741-127279818 (-)



Homology
more
  • Human Ortholog
    RILPL1, Rab interacting lysosomal protein like 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RILPL1, Rab interacting lysosomal protein like 1
  • Synonyms
    GOSPEL, OPDM4, RLP1
  • Links
    NCBI Gene ID: 353116
    neXtProt AC: NX_Q5EBL4
    UniProt: Q5EBL4

  • Chr Location
    12q24.31; chr12:123470054-123533719 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human RILPL1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    869
  • Tissues
    29
  • cDNA Data
    47
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000029392 Ensembl Gene Model | MGI Sequence Detail 38312 C57BL/6J ±  kb
transcript ENSMUST00000062153 Ensembl | MGI Sequence Detail 2249 Not Applicable  
polypeptide ENSMUSP00000050014 Ensembl | MGI Sequence Detail 406 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 50
    cDNA 47
    Primer pair 2
    Other 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:1923435
References
more
  • Summaries
    All 47
    Developmental Gene Expression 4
    Gene Ontology 8
    Phenotypes 14
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory