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Ccdc125 Gene Detail
Summary
  • Symbol
    Ccdc125
  • Name
    coiled-coil domain containing 125
  • Synonyms
    5830436D01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923291
    NCBI Gene: 76041
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:100806225-100833748 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 53.23 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1073 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923291
 protein coding gene Chr13:100805442-100833748 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020891
 protein coding gene Chr13:102599725-102627402 (+)
A/J MGP_AJ_G0020842
 protein coding gene Chr13:98609587-98638528 (+)
AKR/J MGP_AKRJ_G0020817
 protein coding gene Chr13:101644128-101662414 (+)
BALB/cJ MGP_BALBcJ_G0020842
 protein coding gene Chr13:99347478-99365983 (+)
C3H/HeJ MGP_C3HHeJ_G0020631
 protein coding gene Chr13:101343048-101372284 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021276
 protein coding gene Chr13:105655283-105683608 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018846
 protein coding gene Chr13:94432542-94461811 (+)
CAST/EiJ MGP_CASTEiJ_G0020150
 protein coding gene Chr13:100810333-100844561 (+)
CBA/J MGP_CBAJ_G0020593
 protein coding gene Chr13:109826017-109857230 (+)
DBA/2J MGP_DBA2J_G0020717
 protein coding gene Chr13:98391651-98414601 (+)
FVB/NJ MGP_FVBNJ_G0020699
 protein coding gene Chr13:97140663-97158980 (+)
LP/J MGP_LPJ_G0020791
 protein coding gene Chr13:102615744-102645238 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020727
 protein coding gene Chr13:110067789-110096422 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021315
 protein coding gene Chr13:101096846-101124821 (+)
PWK/PhJ MGP_PWKPhJ_G0019903
 protein coding gene Chr13:97115985-97144780 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019725
 protein coding gene Chr13:97323342-97353279 (+)
WSB/EiJ MGP_WSBEiJ_G0020208
 protein coding gene Chr13:101557190-101588505 (+)



Homology
more
  • Human Ortholog
    CCDC125, coiled-coil domain containing 125
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCDC125, coiled-coil domain containing 125
  • Synonyms
    KENAE
  • Links
    NCBI Gene ID: 202243
    neXtProt AC: NX_Q86Z20
    UniProt: Q86Z20

  • Chr Location
    5q13.2; chr5:69273039-69332809 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    15
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000048924 Ensembl Gene Model | MGI Sequence Detail 27524 C57BL/6J ±  kb
transcript ENSMUST00000057325 Ensembl | MGI Sequence Detail 2413 Not Applicable  
polypeptide ENSMUSP00000058484 Ensembl | MGI Sequence Detail 500 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 2
Other
Accession IDs
less
MGI:2145321
References
more
  • Summaries
    All 34
    Diseases 1
    Gene Ontology 4
    Phenotypes 13
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:358278 Yang Y, et al., Erythrocytic alpha-Synuclein and the Gut Microbiome: Kindling of the Gut-Brain Axis in Parkinson's Disease. Mov Disord. 2024 Jan;39(1):40-52
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory