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Prrc2b Gene Detail
Summary
  • Symbol
    Prrc2b
  • Name
    proline-rich coiled-coil 2B
  • Synonyms
    5830434P21Rik, Bat2l, mKIAA0515
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923304
    NCBI Gene: 227723
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:32041094-32124549 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 22.05 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2051 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923304
 protein coding gene Chr2:32041002-32124549 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025597
 protein coding gene Chr2:30571724-30669207 (+)
A/J MGP_AJ_G0025575
 protein coding gene Chr2:29290528-29375573 (+)
AKR/J MGP_AKRJ_G0025544
 protein coding gene Chr2:30300448-30391944 (+)
BALB/cJ MGP_BALBcJ_G0025571
 protein coding gene Chr2:29414544-29499436 (+)
C3H/HeJ MGP_C3HHeJ_G0025332
 protein coding gene Chr2:30226257-30313469 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026016
 protein coding gene Chr2:31520704-31605767 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023424
 protein coding gene Chr2:28027149-28110890 (+)
CAST/EiJ MGP_CASTEiJ_G0024794
 protein coding gene Chr2:30158159-30248040 (+)
CBA/J MGP_CBAJ_G0025309
 protein coding gene Chr2:32709044-32793689 (+)
DBA/2J MGP_DBA2J_G0025442
 protein coding gene Chr2:29058767-29143158 (+)
FVB/NJ MGP_FVBNJ_G0025405
 protein coding gene Chr2:28930726-29015537 (+)
LP/J MGP_LPJ_G0025528
 protein coding gene Chr2:30457854-30543926 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025435
 protein coding gene Chr2:32373628-32459415 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026074
 protein coding gene Chr2:30214101-30301382 (+)
PWK/PhJ MGP_PWKPhJ_G0024541
 protein coding gene Chr2:28961555-29045321 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024341
 protein coding gene Chr2:30362722-30455740 (+)
WSB/EiJ MGP_WSBEiJ_G0024862
 protein coding gene Chr2:30390366-30475290 (+)



Homology
more
  • Human Ortholog
    PRRC2B, proline rich coiled-coil 2B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PRRC2B, proline rich coiled-coil 2B
  • Synonyms
    BAT2L, BAT2L1, KIAA0515, LQFBS-1
  • Links
    NCBI Gene ID: 84726
    neXtProt AC: NX_Q5JSZ5
    UniProt: Q5JSZ5

  • Chr Location
    9q34.13; chr9:131373636-131500197 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    28 phenotypes from 1 allele in 1 genetic background
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    812
  • Tissues
    20
  • cDNA Data
    15
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000039262 Ensembl Gene Model | MGI Sequence Detail 83456 C57BL/6J ±  kb
    transcript ENSMUST00000069817 Ensembl | MGI Sequence Detail 10671 Not Applicable  
    polypeptide ENSMUSP00000064892 Ensembl | MGI Sequence Detail 2230 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 16
      cDNA 16

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:2138850
    References
    more
    • Summaries
      All 45
      Developmental Gene Expression 5
      Gene Ontology 1
      Phenotypes 16
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:350444 Martinez-Mayer J, et al., Knockout mice with pituitary malformations help identify human cases of hypopituitarism. Genome Med. 2024 May 31;16(1):75
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory