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Tmem182 Gene Detail
Summary
  • Symbol
    Tmem182
  • Name
    transmembrane protein 182
  • Synonyms
    2310079P10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923725
    NCBI Gene: 381339
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:40844761-40896047 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 20.01 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1907 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923725
 protein coding gene Chr1:40844738-40896047 (+)
129S1/SvImJ MGP_129S1SvImJ_G0015973
 protein coding gene Chr1:39622030-39675006 (+)
A/J MGP_AJ_G0015957
 protein coding gene Chr1:38498944-38551269 (+)
AKR/J MGP_AKRJ_G0015912
 protein coding gene Chr1:38970224-39024153 (+)
BALB/cJ MGP_BALBcJ_G0015911
 protein coding gene Chr1:38148984-38199071 (+)
C3H/HeJ MGP_C3HHeJ_G0015744
 protein coding gene Chr1:39291305-39346579 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016364
 protein coding gene Chr1:41283903-41335649 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014086
 protein coding gene Chr1:35406710-35456509 (+)
CAST/EiJ MGP_CASTEiJ_G0015325
 protein coding gene Chr1:39181402-39234568 (+)
CBA/J MGP_CBAJ_G0015716
 protein coding gene Chr1:42486364-42542284 (+)
DBA/2J MGP_DBA2J_G0015817
 protein coding gene Chr1:37777126-37828557 (+)
FVB/NJ MGP_FVBNJ_G0015819
 protein coding gene Chr1:37314991-37364970 (+)
LP/J MGP_LPJ_G0015887
 protein coding gene Chr1:39971004-40022904 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0015839
 protein coding gene Chr1:44460589-44526140 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016411
 protein coding gene Chr1:39137890-39190578 (+)
PWK/PhJ MGP_PWKPhJ_G0015108
 protein coding gene Chr1:37594727-37646297 (+)
SPRET/EiJ MGP_SPRETEiJ_G0014890
 protein coding gene Chr1:39110833-39161553 (+)
WSB/EiJ MGP_WSBEiJ_G0015387
 protein coding gene Chr1:39112162-39162466 (+)



Homology
more
  • Human Ortholog
    TMEM182, transmembrane protein 182
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM182, transmembrane protein 182
  • Links
    NCBI Gene ID: 130827
    neXtProt AC: NX_Q6ZP80
    UniProt: Q6ZP80

  • Chr Location
    2q12.1; chr2:102736905-103019900 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null mice show increased body weight, muscle mass, muscle fiber number, and muscle fiber diameter and accelerated skeletal muscle regeneration.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000079588 Ensembl Gene Model | MGI Sequence Detail 51287 C57BL/6J ±  kb
    transcript ENSMUST00000114765 Ensembl | MGI Sequence Detail 2716 Not Applicable  
    polypeptide ENSMUSP00000110413 Ensembl | MGI Sequence Detail 229 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 3
      cDNA 3

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2138224
    References
    more
    • Summaries
      All 29
      Gene Ontology 3
      Phenotypes 9
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    10/29/2024
    MGI 6.24     		The Jackson Laboratory