About   Help   FAQ
Cntd1 Gene Detail
Summary
  • Symbol
    Cntd1
  • Name
    cyclin N-terminal domain containing 1
  • Synonyms
    1700051C09Rik, 5430417M23Rik, MGC:11788
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923965
    NCBI Gene: 68107
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:101170029-101179527 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 64.56 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    290 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923965
 protein coding gene Chr11:101169838-101187143 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019192
 protein coding gene Chr11:104122171-104140773 (+)
A/J MGP_AJ_G0019160
 protein coding gene Chr11:99746004-99763279 (+)
AKR/J MGP_AKRJ_G0019129
 protein coding gene Chr11:102846786-102864039 (+)
BALB/cJ MGP_BALBcJ_G0019134
 protein coding gene Chr11:100232951-100250202 (+)
C3H/HeJ MGP_C3HHeJ_G0018943
 protein coding gene Chr11:103021065-103039113 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019583
 protein coding gene Chr11:107372692-107391375 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017209
 protein coding gene Chr11:97159369-97176618 (+)
CAST/EiJ MGP_CASTEiJ_G0018497
 protein coding gene Chr11:104009482-104026957 (+)
CBA/J MGP_CBAJ_G0018912
 protein coding gene Chr11:111812208-111829475 (+)
DBA/2J MGP_DBA2J_G0019024
 protein coding gene Chr11:99275125-99292650 (+)
FVB/NJ MGP_FVBNJ_G0019014
 protein coding gene Chr11:98821357-98839005 (+)
LP/J MGP_LPJ_G0019093
 protein coding gene Chr11:104667180-104684467 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019045
 protein coding gene Chr11:111367698-111386933 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019621
 protein coding gene Chr11:103173884-103191660 (+)
PWK/PhJ MGP_PWKPhJ_G0018260
 protein coding gene Chr11:100329563-100347106 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018052
 protein coding gene Chr11:102911861-102929101 (+)
WSB/EiJ MGP_WSBEiJ_G0018546
 protein coding gene Chr11:103170157-103188249 (+)



Homology
more
  • Human Ortholog
    CNTD1, cyclin N-terminal domain containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CNTD1, cyclin N-terminal domain containing 1
  • Synonyms
    CNTD, COSA1
  • Links
    NCBI Gene ID: 124817
    neXtProt AC: NX_Q8N815
    UniProt: Q8N815

  • Chr Location
    17q21.2-q21.31; chr17:42798785-42811587 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 4 alleles in 3 genetic backgrounds
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null mice are sterile and show defects in meiosis and germ cell production.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    7
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 68107 NCBI Gene Model | MGI Sequence Detail 9499 C57BL/6J ±  kb
    transcript NM_026562 RefSeq | MGI Sequence Detail 2228 C57BL/6  
    polypeptide Q9D995 UniProt | EBI | MGI Sequence Detail 334 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 8
      cDNA 8

      Microarray probesets 8
    Other
    Accession IDs
    less
    MGI:1915357
    References
    more
    • Summaries
      All 38
      Gene Ontology 5
      Phenotypes 15
    • Earliest
      J:64816 Liang XH, et al., Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein. J Virol. 1998 Nov;72(11):8586-96
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    11/05/2024
    MGI 6.24     		The Jackson Laboratory