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Sult2a8 Gene Detail
Summary
  • Symbol
    Sult2a8
  • Name
    sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 8
  • Synonyms
    2810007J24Rik, mL-STL
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924221
    NCBI Gene: 76971
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:14144611-14180694 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 8.20 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    781 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924221
 protein coding gene Chr7:14144611-14180705 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031683
 protein coding gene Chr7:11939751-11980504 (-)
A/J MGP_AJ_G0031657
 protein coding gene Chr7:11660698-11698992 (-)
AKR/J MGP_AKRJ_G0031580
 protein coding gene Chr7:11993632-12029375 (-)
BALB/cJ MGP_BALBcJ_G0031662
 protein coding gene Chr7:11857628-11894195 (-)
C3H/HeJ MGP_C3HHeJ_G0031383
 protein coding gene Chr7:12176454-12212099 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032126
 protein coding gene Chr7:12530359-12568595 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029212
 protein coding gene Chr7:13429986-13467364 (-)
CAST/EiJ MGP_CASTEiJ_G0030738
 protein coding gene Chr7:9371517-9410288 (-)
CBA/J MGP_CBAJ_G0031341
 protein coding gene Chr7:12819626-12858396 (-)
DBA/2J MGP_DBA2J_G0031499
 protein coding gene Chr7:11622409-11657657 (-)
FVB/NJ MGP_FVBNJ_G0031455
 protein coding gene Chr7:11573805-11610481 (-)
LP/J MGP_LPJ_G0031585
 protein coding gene Chr7:12002580-12050520 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031490
 protein coding gene Chr7:12995028-13039457 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032156
 protein coding gene Chr7:11748602-11789095 (-)
PWK/PhJ MGP_PWKPhJ_G0030463
 protein coding gene Chr7:9794287-9832953 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030291
 protein coding gene Chr7:7478867-7520369 (-)
WSB/EiJ MGP_WSBEiJ_G0030835
 protein coding gene Chr7:11813132-11846989 (-)



Homology
more
  • Human Ortholog
    SULT2A1, sulfotransferase family 2A member 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SULT2A1, sulfotransferase family 2A member 1
  • Synonyms
    DHEAS, DHEA-ST, DHEA-ST8, HST, hSTa, ST2, ST2A1, ST2A3, STD, SULT2A3
  • Links
    NCBI Gene ID: 6822
    neXtProt AC: NX_Q06520
    UniProt: Q06520

  • Chr Location
    19q13.33; chr19:47870467-47886315 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human SULT2A1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    22
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    852
  • Tissues
    19
  • cDNA Data
    9
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000030378 Ensembl Gene Model | MGI Sequence Detail 36084 C57BL/6J ±  kb
    transcript ENSMUST00000168252 Ensembl | MGI Sequence Detail 2097 Not Applicable  
    polypeptide ENSMUSP00000128428 Ensembl | MGI Sequence Detail 282 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 11
      cDNA 9
      Primer pair 2

      Microarray probesets 4
    References
    more
    • Summaries
      All 32
      Developmental Gene Expression 2
      Gene Ontology 7
      Phenotypes 7
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory