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Ccdc183 Gene Detail
Summary
  • Symbol
    Ccdc183
  • Name
    coiled-coil domain containing 183
  • Synonyms
    4921530D09Rik, Cccd183
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924308
    NCBI Gene: 77058
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:25498647-25507690 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 17.54 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    291 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924308
 protein coding gene Chr2:25498641-25507690 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025459
 protein coding gene Chr2:23517614-23528369 (-)
A/J MGP_AJ_G0025436
 protein coding gene Chr2:22598148-22607103 (-)
AKR/J MGP_AKRJ_G0025406
 protein coding gene Chr2:23365768-23374749 (-)
BALB/cJ MGP_BALBcJ_G0025432
 protein coding gene Chr2:22718029-22727746 (-)
C3H/HeJ MGP_C3HHeJ_G0025193
 protein coding gene Chr2:23298791-23307447 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025876
 protein coding gene Chr2:24255250-24268119 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023287
 protein coding gene Chr2:21507534-21516428 (-)
CAST/EiJ MGP_CASTEiJ_G0024656
 protein coding gene Chr2:23165079-23173807 (-)
CBA/J MGP_CBAJ_G0025171
 protein coding gene Chr2:25093397-25108204 (-)
DBA/2J MGP_DBA2J_G0025304
 protein coding gene Chr2:22445053-22454745 (-)
FVB/NJ MGP_FVBNJ_G0025266
 protein coding gene Chr2:22192465-22201321 (-)
LP/J MGP_LPJ_G0025390
 protein coding gene Chr2:23450196-23458951 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025297
 protein coding gene Chr2:25286098-25295079 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025935
 protein coding gene Chr2:23313805-23326709 (-)
PWK/PhJ MGP_PWKPhJ_G0024404
 protein coding gene Chr2:22259085-22268369 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024204
 protein coding gene Chr2:23451205-23460308 (-)
WSB/EiJ MGP_WSBEiJ_G0024725
 protein coding gene Chr2:23378994-23389050 (-)



Homology
more
  • Human Ortholog
    CCDC183, coiled-coil domain containing 183
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCDC183, coiled-coil domain containing 183
  • Synonyms
    bA216L13.7, KIAA1984, PARF
  • Links
    NCBI Gene ID: 84960
    neXtProt AC: NX_Q5T5S1
    UniProt: Q5T5S1

  • Chr Location
    9q34.3; chr9:136796338-136807741 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    25 phenotypes from 2 alleles in 2 genetic backgrounds
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele are exhibit male infertility associated with small testes. severe defects in sperm morphology and motility, cytoplasmic invagination failure and axonemal microtubule collapse during spermiogenesis, and ectopic localization of the sperm fibrous sheath and outer dense fibers.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

Cellular Component
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000026940 Ensembl Gene Model | MGI Sequence Detail 9044 C57BL/6J ±  kb
    transcript ENSMUST00000028309 Ensembl | MGI Sequence Detail 1719 Not Applicable  
    polypeptide ENSMUSP00000028309 Ensembl | MGI Sequence Detail 534 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 5
      cDNA 5

      Microarray probesets 5
    References
    more
    • Summaries
      All 25
      Phenotypes 6
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory