About   Help   FAQ
Asb8 Gene Detail
Summary
  • Symbol
    Asb8
  • Name
    ankyrin repeat and SOCS box-containing 8
  • Synonyms
    4930539L19Rik, C430011H06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925791
    NCBI Gene: 78541
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:98032518-98063476 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 54.13 cM, cytoband F2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    934 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925791
 protein coding gene Chr15:98032518-98063506 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022286
 protein coding gene Chr15:99828622-99860336 (-)
A/J MGP_AJ_G0022245
 protein coding gene Chr15:95877750-95908202 (-)
AKR/J MGP_AKRJ_G0022220
 protein coding gene Chr15:98771089-98802029 (-)
BALB/cJ MGP_BALBcJ_G0022251
 protein coding gene Chr15:96102489-96133407 (-)
C3H/HeJ MGP_C3HHeJ_G0022021
 protein coding gene Chr15:98844578-98876279 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022696
 protein coding gene Chr15:103511939-103544185 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020222
 protein coding gene Chr15:91828719-91860137 (-)
CAST/EiJ MGP_CASTEiJ_G0021543
 protein coding gene Chr15:99725990-99757296 (-)
CBA/J MGP_CBAJ_G0021988
 protein coding gene Chr15:106977273-107007981 (-)
DBA/2J MGP_DBA2J_G0022115
 protein coding gene Chr15:95328856-95359600 (-)
FVB/NJ MGP_FVBNJ_G0022094
 protein coding gene Chr15:94318681-94350058 (-)
LP/J MGP_LPJ_G0022186
 protein coding gene Chr15:99939751-99970792 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022114
 protein coding gene Chr15:111084852-111116470 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022711
 protein coding gene Chr15:98921691-98955026 (-)
PWK/PhJ MGP_PWKPhJ_G0021284
 protein coding gene Chr15:95434697-95466608 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021118
 protein coding gene Chr15:98705887-98744053 (-)
WSB/EiJ MGP_WSBEiJ_G0021592
 protein coding gene Chr15:99439967-99470227 (-)



Homology
more
  • Human Ortholog
    ASB8, ankyrin repeat and SOCS box containing 8
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ASB8, ankyrin repeat and SOCS box containing 8
  • Synonyms
    PP14212
  • Links
    NCBI Gene ID: 140461
    neXtProt AC: NX_Q9H765
    UniProt: Q9H765

  • Chr Location
    12q13.11; chr12:48147789-48181213 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    29 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    766
  • Tissues
    44
  • cDNA Data
    52
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 78541 NCBI Gene Model | MGI Sequence Detail 30959 C57BL/6J ±  kb
transcript NM_001170711 RefSeq | MGI Sequence Detail 2176 C57BL/6  
polypeptide Q91ZT9 UniProt | EBI | MGI Sequence Detail 288 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 52
    cDNA 52

    Microarray probesets 3
Other
Accession IDs
less
MGI:1922488, MGI:2146058
References
more
  • Summaries
    All 57
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 3
    Phenotypes 29
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory