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Nup160 Gene Detail
Summary
  • Symbol
    Nup160
  • Name
    nucleoporin 160
  • Synonyms
    2810011M03Rik, Gtl1-13
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926227
    NCBI Gene: 59015
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:90507559-90566672 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 50.32 cM, cytoband E1
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1200 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926227
 protein coding gene Chr2:90504405-90570217 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026130
 protein coding gene Chr2:91947218-92007785 (+)
A/J MGP_AJ_G0026091
 protein coding gene Chr2:88279973-88340185 (+)
AKR/J MGP_AKRJ_G0026072
 protein coding gene Chr2:90722352-90783842 (+)
BALB/cJ MGP_BALBcJ_G0026100
 protein coding gene Chr2:88435536-88495271 (+)
C3H/HeJ MGP_C3HHeJ_G0025851
 protein coding gene Chr2:90995032-91058332 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026551
 protein coding gene Chr2:95182063-95246304 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023941
 protein coding gene Chr2:84798157-84862375 (+)
CAST/EiJ MGP_CASTEiJ_G0025316
 protein coding gene Chr2:91502532-91563318 (+)
CBA/J MGP_CBAJ_G0025829
 protein coding gene Chr2:98424557-98491220 (+)
DBA/2J MGP_DBA2J_G0025965
 protein coding gene Chr2:87879207-87938397 (+)
FVB/NJ MGP_FVBNJ_G0025928
 protein coding gene Chr2:86975547-87035663 (+)
LP/J MGP_LPJ_G0026069
 protein coding gene Chr2:92152877-92217364 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025954
 protein coding gene Chr2:101488086-101548439 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026605
 protein coding gene Chr2:90770025-90830986 (+)
PWK/PhJ MGP_PWKPhJ_G0025051
 protein coding gene Chr2:87597744-87658586 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024852
 protein coding gene Chr2:90356920-90420415 (+)
WSB/EiJ MGP_WSBEiJ_G0025383
 protein coding gene Chr2:91350317-91414512 (+)



Homology
more
  • Human Ortholog
    NUP160, nucleoporin 160
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NUP160, nucleoporin 160
  • Synonyms
    NPHS19
  • Links
    NCBI Gene ID: 23279
    neXtProt AC: NX_Q12769
    UniProt: Q12769

  • Chr Location
    11p11.2; chr11:47778087-47848555 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human NUP160 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    116
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000051329 Ensembl Gene Model | MGI Sequence Detail 59114 C57BL/6J ±  kb
transcript ENSMUST00000057481 Ensembl | MGI Sequence Detail 5684 Not Applicable  
polypeptide ENSMUSP00000059289 Ensembl | MGI Sequence Detail 1402 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 118
    cDNA 117
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:1917661, MGI:2138773, MGI:2139185
References
more
  • Summaries
    All 48
    Gene Ontology 8
    Phenotypes 14
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:301567 Sakuma S, et al., Inhibition of Nuclear Pore Complex Formation Selectively Induces Cancer Cell Death. Cancer Discov. 2021 Jan;11(1):176-193
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory