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Sult2b1 Gene Detail
Summary
  • Symbol
    Sult2b1
  • Name
    sulfotransferase family, cytosolic, 2B, member 1
  • Synonyms
    Gm5897, SULT2B
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926342
    NCBI Gene: 54200
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:45379405-45409096 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 29.47 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1058 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926342
 protein coding gene Chr7:45379405-45434093 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032246
 protein coding gene Chr7:46040697-46072217 (-)
A/J MGP_AJ_G0032225
 protein coding gene Chr7:45125955-45156407 (-)
AKR/J MGP_AKRJ_G0032161
 protein coding gene Chr7:46380522-46413212 (-)
BALB/cJ MGP_BALBcJ_G0032237
 protein coding gene Chr7:45122268-45151994 (-)
C3H/HeJ MGP_C3HHeJ_G0031952
 protein coding gene Chr7:46872346-46906744 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032729
 protein coding gene Chr7:48290747-48334384 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029743
 protein coding gene Chr7:47680369-47709625 (-)
CAST/EiJ MGP_CASTEiJ_G0031280
 protein coding gene Chr7:38313844-38343028 (-)
CBA/J MGP_CBAJ_G0031917
 protein coding gene Chr7:49899687-49953493 (-)
DBA/2J MGP_DBA2J_G0032075
 protein coding gene Chr7:44806551-44835423 (-)
FVB/NJ MGP_FVBNJ_G0032026
 protein coding gene Chr7:44580311-44610076 (-)
LP/J MGP_LPJ_G0032153
 protein coding gene Chr7:46746246-46779352 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032063
 protein coding gene Chr7:48581838-48620977 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032745
 protein coding gene Chr7:45592745-45625124 (-)
PWK/PhJ MGP_PWKPhJ_G0031003
 protein coding gene Chr7:38174970-38206650 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030841
 protein coding gene Chr7:33623289-33657547 (-)
WSB/EiJ MGP_WSBEiJ_G0031398
 protein coding gene Chr7:46095786-46127878 (-)



Homology
more
  • Human Ortholog
    SULT2B1, sulfotransferase family 2B member 1
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SULT2B1, sulfotransferase family 2B member 1
  • Synonyms
    ARCI14, HSST2
  • Links
    NCBI Gene ID: 6820
    neXtProt AC: NX_O00204
    UniProt: O00204

  • Chr Location
    19q13.33; chr19:48552172-48599427 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human SULT2B1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele lack cholesterol sulfate in the dermis but otherwise appear to have normal lipid metabolism.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    22
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    861
  • Tissues
    117
  • cDNA Data
    10
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 54200 NCBI Gene Model | MGI Sequence Detail 29692 C57BL/6J ±  kb
transcript NM_001360784 RefSeq | MGI Sequence Detail 1271 C57BL/6  
polypeptide O35400 UniProt | EBI | MGI Sequence Detail 338 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 10
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
less
MGI:2141922, MGI:2142299, MGI:3648578
References
more
  • Summaries
    All 47
    Developmental Gene Expression 3
    Gene Ontology 7
    Phenotypes 14
  • Earliest
    J:48327 Sakakibara Y, et al., Molecular cloning, expression, and functional characterization of novel mouse sulfotransferases. Biochem Biophys Res Commun. 1998 Jun 29;247(3):681-6
  • Latest
    J:345243 Morino K, et al., Cholesterol sulfate limits neutrophil recruitment and gut inflammation during mucosal injury. Front Immunol. 2023;14:1131146
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory