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Myo1g Gene Detail
Summary
  • Symbol
    Myo1g
  • Name
    myosin IG
  • Synonyms
    E430002D17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1927091
    NCBI Gene: 246177
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:6456548-6470960 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 4.30 cM, cytoband A1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    386 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1927091
 protein coding gene Chr11:6456548-6470965 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018025
 protein coding gene Chr11:3645799-3660195 (-)
A/J MGP_AJ_G0017998
 protein coding gene Chr11:3483517-3497928 (-)
AKR/J MGP_AKRJ_G0017962
 protein coding gene Chr11:3663061-3677472 (-)
BALB/cJ MGP_BALBcJ_G0017966
 protein coding gene Chr11:3496226-3510630 (-)
C3H/HeJ MGP_C3HHeJ_G0017779
 protein coding gene Chr11:3535134-3549587 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018418
 protein coding gene Chr11:3736718-3751135 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016076
 protein coding gene Chr11:3369109-3383676 (-)
CAST/EiJ MGP_CASTEiJ_G0017341
 protein coding gene Chr11:3537214-3551826 (-)
CBA/J MGP_CBAJ_G0017754
 protein coding gene Chr11:4160913-4175330 (-)
DBA/2J MGP_DBA2J_G0017864
 protein coding gene Chr11:3387322-3401739 (-)
FVB/NJ MGP_FVBNJ_G0017856
 protein coding gene Chr11:3419495-3433905 (-)
LP/J MGP_LPJ_G0017935
 protein coding gene Chr11:3716424-3730828 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017882
 protein coding gene Chr11:3714841-3729252 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018458
 protein coding gene Chr11:3675058-3689475 (-)
PWK/PhJ MGP_PWKPhJ_G0017121
 protein coding gene Chr11:3433953-3448349 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016918
 protein coding gene Chr11:3619644-3634078 (-)
WSB/EiJ MGP_WSBEiJ_G0017395
 protein coding gene Chr11:3499584-3513980 (-)



Homology
more
  • Human Ortholog
    MYO1G, myosin IG
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MYO1G, myosin IG
  • Synonyms
    HA2, HLA-HA2, MHAG
  • Links
    NCBI Gene ID: 64005
    neXtProt AC: NX_B0I1T2
    UniProt: B0I1T2

  • Chr Location
    7p13; chr7:44962662-44979088 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotypes from 2 alleles in 3 genetic backgrounds
    1 phenotype from multigenic genotypes
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit reduced B cell spreading, migration and homing and impaired T cell motility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    34
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    38
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 246177 NCBI Gene Model | MGI Sequence Detail 14413 C57BL/6J ±  kb
    transcript NM_178440 RefSeq | MGI Sequence Detail 3307 C57BL/6  
    polypeptide Q5SUA5 UniProt | EBI | MGI Sequence Detail 1024 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 38
      cDNA 38

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2442411
    References
    more
    • Summaries
      All 42
      Gene Ontology 9
      Phenotypes 13
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory