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Morf4l2 Gene Detail
Summary
  • Symbol
    Morf4l2
  • Name
    mortality factor 4 like 2
  • Synonyms
    2410017O14Rik, mKIAA0026, Sid393p
  • Feature Type
    protein coding gene
  • IDs
    MGI:1927167
    NCBI Gene: 56397
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:135633691-135644435 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 59.10 cM, cytoband F1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    270 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1927167
 protein coding gene ChrX:135633691-135644439 (-)
129S1/SvImJ MGP_129S1SvImJ_G0036103
 protein coding gene ChrX:134143275-134154738 (-)
A/J MGP_AJ_G0036084
 protein coding gene ChrX:133537180-133547809 (-)
AKR/J MGP_AKRJ_G0036008
 protein coding gene ChrX:137808427-137822099 (-)
BALB/cJ MGP_BALBcJ_G0036073
 protein coding gene ChrX:131940129-131950212 (-)
C3H/HeJ MGP_C3HHeJ_G0035782
 protein coding gene ChrX:134180886-134191534 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036597
 protein coding gene ChrX:138038065-138049425 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033424
 protein coding gene ChrX:125491884-125501914 (-)
CAST/EiJ MGP_CASTEiJ_G0035070
 protein coding gene ChrX:114973696-114985073 (-)
CBA/J MGP_CBAJ_G0035758
 protein coding gene ChrX:142290279-142302318 (-)
DBA/2J MGP_DBA2J_G0035915
 protein coding gene ChrX:132839249-132850735 (-)
FVB/NJ MGP_FVBNJ_G0035849
 protein coding gene ChrX:132049559-132059458 (-)
LP/J MGP_LPJ_G0036009
 protein coding gene ChrX:135110933-135124361 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035885
 protein coding gene ChrX:149584149-149594139 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036634
 protein coding gene ChrX:133513288-133523686 (-)
PWK/PhJ MGP_PWKPhJ_G0034763
 protein coding gene ChrX:112004524-112014850 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034591
 protein coding gene ChrX:115599269-115610108 (-)
WSB/EiJ MGP_WSBEiJ_G0035205
 protein coding gene ChrX:131831479-131842199 (-)



Homology
more
  • Human Ortholog
    MORF4L2, mortality factor 4 like 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MORF4L2, mortality factor 4 like 2
  • Synonyms
    MORFL2, MRGX
  • Links
    NCBI Gene ID: 9643
    neXtProt AC: NX_Q15014
    UniProt: Q15014

  • Chr Location
    Xq22.2; chrX:103675496-103688158 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    2 phenotypes from multigenic genotypes
    11 phenotype references
Homozygous null females and hemizygous null males are healthy and fertile with no obvious abnormalities and null MEFs have normal growth rates.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    22
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    758
  • Tissues
    32
  • cDNA Data
    23
  • Literature Summary
    4
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 56397 NCBI Gene Model | MGI Sequence Detail 10745 C57BL/6J ±  kb
transcript NM_019768 RefSeq | MGI Sequence Detail 1954 C57BL/6  
polypeptide Q9R0Q4 UniProt | EBI | MGI Sequence Detail 288 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 27
    cDNA 24
    Primer pair 3

    Microarray probesets 5
Other
Accession IDs
less
MGI:1919211
References
more
  • Summaries
    All 42
    Developmental Gene Expression 4
    Diseases 1
    Gene Ontology 7
    Phenotypes 11
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:294372 Brandsma I, et al., HSF2BP Interacts with a Conserved Domain of BRCA2 and Is Required for Mouse Spermatogenesis. Cell Rep. 2019 Jun 25;27(13):3790-3798.e7
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory