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Ms4a8a Gene Detail
Summary
  • Symbol
    Ms4a8a
  • Name
    membrane-spanning 4-domains, subfamily A, member 8A
  • Synonyms
    2010004L09Rik, CD20L5, Ms4a8
  • Feature Type
    protein coding gene
  • IDs
    MGI:1927657
    NCBI Gene: 64381
  • Member of
    Ms4ac cluster
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:11044835-11058466 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 7.62 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    390 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1927657
 protein coding gene Chr19:11044835-11058467 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024868
 protein coding gene Chr19:8449263-8462859 (-)
A/J MGP_AJ_G0024836
 protein coding gene Chr19:7893135-7907866 (-)
AKR/J MGP_AKRJ_G0024811
 protein coding gene Chr19:8190470-8203960 (-)
BALB/cJ MGP_BALBcJ_G0024836
 protein coding gene Chr19:7929484-7942998 (-)
C3H/HeJ MGP_C3HHeJ_G0024602
 protein coding gene Chr19:8078496-8092100 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025284
 protein coding gene Chr19:8841368-8854844 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022711
 protein coding gene Chr19:8319950-8335486 (-)
CAST/EiJ MGP_CASTEiJ_G0024075
 protein coding gene Chr19:7733095-7746240 (-)
CBA/J MGP_CBAJ_G0024576
 protein coding gene Chr19:8882949-8898906 (-)
DBA/2J MGP_DBA2J_G0024703
 protein coding gene Chr19:7885165-7898595 (-)
FVB/NJ MGP_FVBNJ_G0024670
 protein coding gene Chr19:7933280-7946943 (-)
LP/J MGP_LPJ_G0024790
 protein coding gene Chr19:8407764-8421643 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024697
 protein coding gene Chr19:8767871-8782505 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025332
 protein coding gene Chr19:8214985-8228611 (-)
PWK/PhJ MGP_PWKPhJ_G0023820
 protein coding gene Chr19:7346951-7361006 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023625
 protein coding gene Chr19:7416077-7432111 (-)
WSB/EiJ MGP_WSBEiJ_G0024137
 protein coding gene Chr19:8100098-8117271 (-)



Homology
more
  • Human Ortholog
    MS4A8, membrane spanning 4-domains A8
  • Vertebrate Orthologs
    20
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MS4A8, membrane spanning 4-domains A8
  • Synonyms
    4SPAN4, CD20L5, MS4A4, MS4A8B
  • Links
    NCBI Gene ID: 83661
    neXtProt AC: NX_Q9BY19
    UniProt: Q9BY19

  • Chr Location
    11q12.2; chr11:60699585-60715807 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    711
  • Tissues
    2
  • cDNA Data
    13
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024730 Ensembl Gene Model | MGI Sequence Detail 13632 C57BL/6J ±  kb
transcript ENSMUST00000025636 Ensembl | MGI Sequence Detail 1081 Not Applicable  
polypeptide ENSMUSP00000025636 Ensembl | MGI Sequence Detail 290 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 3
Other
Accession IDs
less
MGI:1917053, MGI:2147566
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 1
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory