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Krtdap Gene Detail
Summary
  • Symbol
    Krtdap
  • Name
    keratinocyte differentiation associated protein
  • Synonyms
    Kdap, sk221
  • Feature Type
    protein coding gene
  • IDs
    MGI:1928282
    NCBI Gene: 64661
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:30487330-30490514 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 19.24 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    220 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1928282
 protein coding gene Chr7:30487321-30490522 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032045
 protein coding gene Chr7:29801410-29804612 (+)
A/J MGP_AJ_G0032022
 protein coding gene Chr7:28991158-28994359 (+)
AKR/J MGP_AKRJ_G0031955
 protein coding gene Chr7:29734314-29737508 (+)
BALB/cJ MGP_BALBcJ_G0032029
 protein coding gene Chr7:29182460-29185711 (+)
C3H/HeJ MGP_C3HHeJ_G0031748
 protein coding gene Chr7:30199789-30202987 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032495
 protein coding gene Chr7:30781112-30784311 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029545
 protein coding gene Chr7:30010495-30013655 (+)
CAST/EiJ MGP_CASTEiJ_G0031082
 protein coding gene Chr7:23445987-23450383 (+)
CBA/J MGP_CBAJ_G0031714
 protein coding gene Chr7:32233924-32237125 (+)
DBA/2J MGP_DBA2J_G0031866
 protein coding gene Chr7:28741016-28744653 (+)
FVB/NJ MGP_FVBNJ_G0031823
 protein coding gene Chr7:28855962-28859170 (+)
LP/J MGP_LPJ_G0031947
 protein coding gene Chr7:30120765-30126934 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031859
 protein coding gene Chr7:31471519-31476292 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032523
 protein coding gene Chr7:29242634-29247513 (+)
PWK/PhJ MGP_PWKPhJ_G0030806
 protein coding gene Chr7:23765558-23768766 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030641
 protein coding gene Chr7:20250538-20253741 (+)
WSB/EiJ MGP_WSBEiJ_G0031192
 protein coding gene Chr7:29649352-29653757 (+)



Homology
more
  • Human Ortholog
    KRTDAP, keratinocyte differentiation associated protein
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KRTDAP, keratinocyte differentiation associated protein
  • Synonyms
    KDAP, UNQ467
  • Links
    NCBI Gene ID: 388533
    neXtProt AC: NX_P60985
    UniProt: P60985

  • Chr Location
    19q13.12; chr19:35487324-35495558 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    711
  • Tissues
    4
  • cDNA Data
    36
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 64661 NCBI Gene Model | MGI Sequence Detail 3185 C57BL/6J ±  kb
transcript NM_001033131 RefSeq | MGI Sequence Detail 462 C57BL/6  
polypeptide Q3V2T4 UniProt | EBI | MGI Sequence Detail 102 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000009590 keratinocyte differentiation-associated protein
    (term hierarchy)
  • InterPro Domains
    IPR028196 Keratinocyte differentiation-associated protein
Molecular
Reagents
less
  • All nucleic 36
    cDNA 36

    Microarray probesets 3
References
more
  • Summaries
    All 34
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:65469 Oomizu S, et al., Kdap, a novel gene associated with the stratification of the epithelium. Gene. 2000 Oct 3;256(1-2):19-27
  • Latest
    J:341969 Jacob T, et al., Molecular and spatial landmarks of early mouse skin development. Dev Cell. 2023 Oct 23;58(20):2140-2162.e5
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory