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Ccl24 Gene Detail
Summary
  • Symbol
    Ccl24
  • Name
    C-C motif chemokine ligand 24
  • Synonyms
    CKb-6, eotaxin-2, MPIF-2, Scya24
  • Feature Type
    protein coding gene
  • IDs
    MGI:1928953
    NCBI Gene: 56221
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:135598791-135601903 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 75.28 cM, cytoband G1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    221 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1928953
 protein coding gene Chr5:135598789-135601977 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030185
 protein coding gene Chr5:140120863-140123975 (-)
A/J MGP_AJ_G0030153
 protein coding gene Chr5:134125074-134128186 (-)
AKR/J MGP_AKRJ_G0030086
 protein coding gene Chr5:138470946-138474058 (-)
BALB/cJ MGP_BALBcJ_G0030163
 protein coding gene Chr5:135462257-135465369 (-)
C3H/HeJ MGP_C3HHeJ_G0029879
 protein coding gene Chr5:139036886-139039998 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030616
 protein coding gene Chr5:145345722-145348832 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027839
 protein coding gene Chr5:128407075-128410446 (-)
CAST/EiJ MGP_CASTEiJ_G0029288
 protein coding gene Chr5:138444456-138447594 (-)
CBA/J MGP_CBAJ_G0029849
 protein coding gene Chr5:151029943-151033055 (-)
DBA/2J MGP_DBA2J_G0030000
 protein coding gene Chr5:134017423-134020533 (-)
FVB/NJ MGP_FVBNJ_G0029955
 protein coding gene Chr5:133160860-133163972 (-)
LP/J MGP_LPJ_G0030088
 protein coding gene Chr5:140564110-140567222 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029987
 protein coding gene Chr5:154019441-154022553 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030656
 protein coding gene Chr5:138228664-138231776 (-)
PWK/PhJ MGP_PWKPhJ_G0029003
 protein coding gene Chr5:133062172-133065275 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028838
 protein coding gene Chr5:135777870-135781015 (-)
WSB/EiJ MGP_WSBEiJ_G0029362
 protein coding gene Chr5:138966735-138969847 (-)



Homology
more
  • Human Ortholog
    CCL24, C-C motif chemokine ligand 24
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCL24, C-C motif chemokine ligand 24
  • Synonyms
    Ckb-6, MPIF-2, MPIF2, SCYA24
  • Links
    NCBI Gene ID: 6369
    neXtProt AC: NX_O00175
    UniProt: O00175

  • Chr Location
    7q11.23; chr7:75810825-75823372 (-)  GRCh38
Human Diseases
more
  • Diseases
    2 with human CCL24 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 2 genetic backgrounds
    5 phenotypes from multigenic genotypes
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mutant mice are born at the expected Mendelian frequency and appear healthy and normal.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    35
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    9
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000004814 Ensembl Gene Model | MGI Sequence Detail 3113 C57BL/6J ±  kb
transcript ENSMUST00000004936 Ensembl | MGI Sequence Detail 1295 Not Applicable  
polypeptide ENSMUSP00000004936 Ensembl | MGI Sequence Detail 119 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 3
References
more
  • Summaries
    All 48
    Gene Ontology 10
    Phenotypes 12
  • Earliest
    J:66327 Zimmermann N, et al., Murine eotaxin-2: A constitutive eosinophil chemokine induced by allergen challenge and IL-4 overexpression. J Immunol. 2000 Nov 15;165(10):5839-46
  • Latest
    J:301128 Lee SH, et al., M2-like, dermal macrophages are maintained via IL-4/CCL24-mediated cooperative interaction with eosinophils in cutaneous leishmaniasis. Sci Immunol. 2020 Apr 10;5(46)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory