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Eef1b2 Gene Detail
Summary
  • Symbol
    Eef1b2
  • Name
    eukaryotic translation elongation factor 1 beta 2
  • Synonyms
    2810017J07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929520
    NCBI Gene: 55949
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:63215990-63219645 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 32.31 cM, cytoband C2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    133 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929520
 protein coding gene Chr1:63215984-63219645 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016086
 protein coding gene Chr1:63319559-63323220 (+)
A/J MGP_AJ_G0016069
 protein coding gene Chr1:61076488-61080149 (+)
AKR/J MGP_AKRJ_G0016026
 protein coding gene Chr1:62757526-62761187 (+)
BALB/cJ MGP_BALBcJ_G0016024
 protein coding gene Chr1:61163374-61167035 (+)
C3H/HeJ MGP_C3HHeJ_G0015856
 protein coding gene Chr1:63036199-63039860 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016477
 protein coding gene Chr1:65752963-65757637 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014198
 protein coding gene Chr1:57194430-57196969 (+)
CAST/EiJ MGP_CASTEiJ_G0015439
 protein coding gene Chr1:62301145-62305531 (+)
CBA/J MGP_CBAJ_G0015828
 protein coding gene Chr1:67855072-67859631 (+)
DBA/2J MGP_DBA2J_G0015929
 protein coding gene Chr1:60491542-60495221 (+)
FVB/NJ MGP_FVBNJ_G0015932
 protein coding gene Chr1:59783965-59787626 (+)
LP/J MGP_LPJ_G0016001
 protein coding gene Chr1:64204246-64207907 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0015953
 protein coding gene Chr1:70760473-70777058 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016524
 protein coding gene Chr1:62741330-62744991 (+)
PWK/PhJ MGP_PWKPhJ_G0015226
 protein coding gene Chr1:59861302-59863792 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015005
 protein coding gene Chr1:62260608-62266601 (+)
WSB/EiJ MGP_WSBEiJ_G0015501
 protein coding gene Chr1:62464802-62470371 (+)



Homology
more
  • Human Ortholog
    EEF1B2, eukaryotic translation elongation factor 1 beta 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    EEF1B2, eukaryotic translation elongation factor 1 beta 2
  • Synonyms
    EEF1B, EEF1B1, EF1B
  • Links
    NCBI Gene ID: 1933
    neXtProt AC: NX_P24534
    UniProt: P24534

  • Chr Location
    2q33.3; chr2:206159585-206162928 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    840
  • Tissues
    72
  • cDNA Data
    529
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 55949 NCBI Gene Model | MGI Sequence Detail 3656 C57BL/6J ±  kb
    transcript NM_018796 RefSeq | MGI Sequence Detail 1933 C57BL/6  
    polypeptide O70251 UniProt | EBI | MGI Sequence Detail 225 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      7 Sequences
    • Protein Ontology
      PR:000006905 elongation factor 1-beta
      (term hierarchy)
    • InterPro Domains
      IPR018940 Elongation factor 1 beta central acidic region, eukaryote
      IPR036282 Glutathione S-transferase, C-terminal domain superfamily
      IPR036219 Translation elongation factor eEF-1beta-like superfamily
      IPR001326 Translation elongation factor EF1B, beta/delta chains, conserved site
      IPR049720 Translation elongation factor EF1B, beta/delta subunit
      IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain
      IPR014717 Translation elongation factor EF1B/small ribosomal subunit protein bS6
    • GlyGen
      O70251 1 site, 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 532
      Genomic 1
      cDNA 530
      Primer pair 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1919870
    References
    more
    • Summaries
      All 44
      Developmental Gene Expression 2
      Gene Ontology 7
      Phenotypes 15
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory