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Cdc42ep2 Gene Detail
Summary
  • Symbol
    Cdc42ep2
  • Name
    CDC42 effector protein 2
  • Synonyms
    1110008C05Rik, Borg1, Cep2, D19Bwg1013e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929744
    NCBI Gene: 104252
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:5967584-5974844 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 4.34 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    277 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929744
 protein coding gene Chr19:5965664-5974844 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024733
 protein coding gene Chr19:2928180-2936067 (-)
A/J MGP_AJ_G0024699
 protein coding gene Chr19:2766714-2773963 (-)
AKR/J MGP_AKRJ_G0024672
 protein coding gene Chr19:2846840-2853812 (-)
BALB/cJ MGP_BALBcJ_G0024699
 protein coding gene Chr19:2760718-2767968 (-)
C3H/HeJ MGP_C3HHeJ_G0024467
 protein coding gene Chr19:2864123-2871262 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025146
 protein coding gene Chr19:2989266-2996519 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022576
 protein coding gene Chr19:2669050-2676876 (-)
CAST/EiJ MGP_CASTEiJ_G0023939
 protein coding gene Chr19:2870304-2877545 (-)
CBA/J MGP_CBAJ_G0024439
 protein coding gene Chr19:3133478-3140738 (-)
DBA/2J MGP_DBA2J_G0024566
 protein coding gene Chr19:2756797-2763928 (-)
FVB/NJ MGP_FVBNJ_G0024532
 protein coding gene Chr19:2759274-2767766 (-)
LP/J MGP_LPJ_G0024652
 protein coding gene Chr19:2891380-2898639 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024562
 protein coding gene Chr19:2952983-2960238 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025194
 protein coding gene Chr19:2861977-2870417 (-)
PWK/PhJ MGP_PWKPhJ_G0023685
 protein coding gene Chr19:2781241-2788544 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023490
 protein coding gene Chr19:2850489-2857895 (-)
WSB/EiJ MGP_WSBEiJ_G0024001
 protein coding gene Chr19:2870802-2878061 (-)



Homology
more
  • Human Ortholog
    CDC42EP2, CDC42 effector protein 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CDC42EP2, CDC42 effector protein 2
  • Synonyms
    BORG1, CEP2
  • Links
    NCBI Gene ID: 10435
    neXtProt AC: NX_O14613
    UniProt: O14613

  • Chr Location
    11q13.1; chr11:65314866-65322417 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    33
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    732
  • Tissues
    16
  • cDNA Data
    7
  • Literature Summary
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 104252 NCBI Gene Model | MGI Sequence Detail 7261 C57BL/6J ±  kb
transcript NM_026772 RefSeq | MGI Sequence Detail 1491 ZRU/MplStud  
polypeptide Q8JZX9 UniProt | EBI | MGI Sequence Detail 214 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 7
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-33946, MGI:106254, MGI:1915823, MGI:2147610
References
more
  • Summaries
    All 36
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 5
  • Earliest
    J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory