About   Help   FAQ
Wdr46 Gene Detail
Summary
  • Symbol
    Wdr46
  • Name
    WD repeat domain 46
  • Synonyms
    2310007I04Rik, Bing4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1931871
    NCBI Gene: 57315
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:34159634-34168671 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 17.98 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1931871
 protein coding gene Chr17:34159608-34168671 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023546
 protein coding gene Chr17:33890066-33899101 (+)
A/J MGP_AJ_G0023507
 protein coding gene Chr17:32723137-32732746 (+)
AKR/J MGP_AKRJ_G0023473
 protein coding gene Chr17:33118769-33127715 (+)
BALB/cJ MGP_BALBcJ_G0023510
 protein coding gene Chr17:32896039-32904970 (+)
C3H/HeJ MGP_C3HHeJ_G0023272
 protein coding gene Chr17:33474148-33483071 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023952
 protein coding gene Chr17:35143130-35152185 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021426
 protein coding gene Chr17:30226108-30234996 (+)
CAST/EiJ MGP_CASTEiJ_G0022774
 protein coding gene Chr17:33550792-33559655 (+)
CBA/J MGP_CBAJ_G0023249
 protein coding gene Chr17:36576060-36584996 (+)
DBA/2J MGP_DBA2J_G0023377
 protein coding gene Chr17:32100406-32109669 (+)
FVB/NJ MGP_FVBNJ_G0023346
 protein coding gene Chr17:31959992-31976717 (+)
LP/J MGP_LPJ_G0023455
 protein coding gene Chr17:34165274-34174309 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023368
 protein coding gene Chr17:35624619-35633379 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023993
 protein coding gene Chr17:33446970-33455891 (+)
PWK/PhJ MGP_PWKPhJ_G0022522
 protein coding gene Chr17:31015051-31024447 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022338
 protein coding gene Chr17:31409938-31418966 (+)
WSB/EiJ MGP_WSBEiJ_G0022834
 protein coding gene Chr17:33484885-33493807 (+)



Homology
more
  • Human Ortholog
    WDR46, WD repeat domain 46
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    WDR46, WD repeat domain 46
  • Synonyms
    BING4, C6orf11, FP221, UTP7
  • Links
    NCBI Gene ID: 9277
    neXtProt AC: NX_O15213
    UniProt: O15213

  • Chr Location
    6p21.32; chr6:33279108-33289247 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    756
  • Tissues
    36
  • cDNA Data
    76
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024312 Ensembl Gene Model | MGI Sequence Detail 9038 C57BL/6J ±  kb
transcript ENSMUST00000025170 Ensembl | MGI Sequence Detail 2229 Not Applicable  
polypeptide ENSMUSP00000025170 Ensembl | MGI Sequence Detail 622 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 78
    Genomic 1
    cDNA 76
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1923674, MGI:2147123, MGI:2147124
References
more
  • Summaries
    All 30
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory