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Dnajb12 Gene Detail
Summary
  • Symbol
    Dnajb12
  • Name
    DnaJ heat shock protein family (Hsp40) member B12
  • Synonyms
    mDj10
  • Feature Type
    protein coding gene
  • IDs
    MGI:1931881
    NCBI Gene: 56709
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:59715405-59735118 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 10, 29.64 cM, cytoband B3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    477 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1931881
protein coding gene Chr10:59715378-59735124 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017261
protein coding gene Chr10:59064841-59085340 (+)
A/J MGP_AJ_G0017239
protein coding gene Chr10:57336444-57356190 (+)
AKR/J MGP_AKRJ_G0017197
protein coding gene Chr10:58803879-58823625 (+)
BALB/cJ MGP_BALBcJ_G0017199
protein coding gene Chr10:57430242-57450331 (+)
C3H/HeJ MGP_C3HHeJ_G0017022
protein coding gene Chr10:58742915-58762894 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017657
protein coding gene Chr10:61186551-61207589 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015348
protein coding gene Chr10:54360670-54380405 (+)
CAST/EiJ MGP_CASTEiJ_G0016593
protein coding gene Chr10:58671348-58691909 (+)
CBA/J MGP_CBAJ_G0016994
protein coding gene Chr10:63361733-63384001 (+)
DBA/2J MGP_DBA2J_G0017099
protein coding gene Chr10:56646685-56667801 (+)
FVB/NJ MGP_FVBNJ_G0017093
protein coding gene Chr10:55883119-55902863 (+)
LP/J MGP_LPJ_G0017174
protein coding gene Chr10:59441166-59460894 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017121
protein coding gene Chr10:65864845-65884911 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017695
protein coding gene Chr10:58630025-58649758 (+)
PWK/PhJ MGP_PWKPhJ_G0016376
protein coding gene Chr10:56454019-56475317 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016159
protein coding gene Chr10:57974450-57994326 (+)
WSB/EiJ MGP_WSBEiJ_G0016657
protein coding gene Chr10:58542908-58562644 (+)



Homology
more
  • Human Ortholog
    DNAJB12, DnaJ heat shock protein family (Hsp40) member B12
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DNAJB12, DnaJ heat shock protein family (Hsp40) member B12
  • Synonyms
    DJ10
  • Links
    NCBI Gene ID: 54788
    neXtProt AC: NX_Q9NXW2
    UniProt: Q9NXW2

  • Chr Location
    10q22.1; chr10:72332830-72355149 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 56709 NCBI Gene Model | MGI Sequence Detail 19714 C57BL/6J ±  kb
    transcript NM_019965 RefSeq | MGI Sequence Detail 3062 C57BL/6  
    polypeptide Q9QYI4 UniProt | EBI | MGI Sequence Detail 376 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 11
      cDNA 11

      Microarray probesets 4
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 1
      Gene Ontology 4
      Phenotypes 17
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    11/19/2024
    MGI 6.24
    The Jackson Laboratory