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Jdp2 Gene Detail
Summary
  • Symbol
    Jdp2
  • Name
    Jun dimerization protein 2
  • Synonyms
    Jundm2, TIF
  • Feature Type
    protein coding gene
  • IDs
    MGI:1932093
    NCBI Gene: 81703
  • Alliance
    gene page
  • Transcription Start Sites
    12 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:85645801-85686652 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 39.74 cM, cytoband D3
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    990 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1932093
 protein coding gene Chr12:85645190-85686652 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019962
 protein coding gene Chr12:86380827-86424985 (+)
A/J MGP_AJ_G0019919
 protein coding gene Chr12:83104862-83146515 (+)
AKR/J MGP_AKRJ_G0019895
 protein coding gene Chr12:85356250-85397023 (+)
BALB/cJ MGP_BALBcJ_G0019899
 protein coding gene Chr12:83445161-83486320 (+)
C3H/HeJ MGP_C3HHeJ_G0019705
 protein coding gene Chr12:85827580-85869982 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020350
 protein coding gene Chr12:88878516-88922981 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017968
 protein coding gene Chr12:79988280-80028808 (+)
CAST/EiJ MGP_CASTEiJ_G0019255
 protein coding gene Chr12:80803965-80849446 (+)
CBA/J MGP_CBAJ_G0019676
 protein coding gene Chr12:92275441-92317933 (+)
DBA/2J MGP_DBA2J_G0019790
 protein coding gene Chr12:82618482-82659820 (+)
FVB/NJ MGP_FVBNJ_G0019777
 protein coding gene Chr12:81588307-81629084 (+)
LP/J MGP_LPJ_G0019864
 protein coding gene Chr12:86255694-86302125 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019816
 protein coding gene Chr12:95113088-95157034 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020383
 protein coding gene Chr12:84961870-85005013 (+)
PWK/PhJ MGP_PWKPhJ_G0019018
 protein coding gene Chr12:77129903-77172313 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018814
 protein coding gene Chr12:79439281-79485600 (+)
WSB/EiJ MGP_WSBEiJ_G0019307
 protein coding gene Chr12:85700730-85744340 (+)



Homology
more
  • Human Ortholog
    JDP2, Jun dimerization protein 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    JDP2, Jun dimerization protein 2
  • Synonyms
    JUNDM2
  • Links
    NCBI Gene ID: 122953
    neXtProt AC: NX_Q8WYK2
    UniProt: Q8WYK2

  • Chr Location
    14q24.3; chr14:75426943-75474111 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    21 phenotypes from 4 alleles in 4 genetic backgrounds
    21 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit increased white adipose tissue differentiation, short tail, and enhanced would healing due to increased cell proliferation.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    31
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    999
  • Tissues
    95
  • cDNA Data
    6
  • Literature Summary
    9
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000034271 Ensembl Gene Model | MGI Sequence Detail 40852 C57BL/6J ±  kb
    transcript ENSMUST00000177587 Ensembl | MGI Sequence Detail 1645 Not Applicable  
    polypeptide ENSMUSP00000136823 Ensembl | MGI Sequence Detail 163 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 7
      cDNA 6
      Primer pair 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 53
      Developmental Gene Expression 9
      Gene Ontology 5
      Phenotypes 21
    • Earliest
      J:67261 Jin C, et al., Identification of mouse Jun dimerization protein 2 as a novel repressor of ATF-2. FEBS Lett. 2001 Jan 26;489(1):34-41
    • Latest
      J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory