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Rnf114 Gene Detail
Summary
  • Symbol
    Rnf114
  • Name
    ring finger protein 114
  • Synonyms
    1110008J21Rik, Zfp313, Znf228
  • Feature Type
    protein coding gene
  • IDs
    MGI:1933159
    NCBI Gene: 81018
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:167334565-167358093 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 87.25 cM, cytoband H3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    713 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1933159
 protein coding gene Chr2:167334565-167358093 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026914
 protein coding gene Chr2:173232127-173260451 (+)
A/J MGP_AJ_G0026881
 protein coding gene Chr2:166098170-166121697 (+)
AKR/J MGP_AKRJ_G0026852
 protein coding gene Chr2:171051564-171076078 (+)
BALB/cJ MGP_BALBcJ_G0026890
 protein coding gene Chr2:166456612-166480194 (+)
C3H/HeJ MGP_C3HHeJ_G0026632
 protein coding gene Chr2:171421609-171447856 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027337
 protein coding gene Chr2:178288125-178311500 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024708
 protein coding gene Chr2:159415829-159439528 (+)
CAST/EiJ MGP_CASTEiJ_G0026090
 protein coding gene Chr2:171885682-171909253 (+)
CBA/J MGP_CBAJ_G0026609
 protein coding gene Chr2:184826258-184849822 (+)
DBA/2J MGP_DBA2J_G0026747
 protein coding gene Chr2:165212745-165236823 (+)
FVB/NJ MGP_FVBNJ_G0026713
 protein coding gene Chr2:163740363-163764205 (+)
LP/J MGP_LPJ_G0026848
 protein coding gene Chr2:173245591-173270771 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026732
 protein coding gene Chr2:188208341-188233049 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027394
 protein coding gene Chr2:170984719-171010823 (+)
PWK/PhJ MGP_PWKPhJ_G0025827
 protein coding gene Chr2:164879917-164904594 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025628
 protein coding gene Chr2:169919153-169942780 (+)
WSB/EiJ MGP_WSBEiJ_G0026163
 protein coding gene Chr2:171892651-171916222 (+)



Homology
more
  • Human Ortholog
    RNF114, ring finger protein 114
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RNF114, ring finger protein 114
  • Synonyms
    PSORS12, ZNF313
  • Links
    NCBI Gene ID: 55905
    neXtProt AC: NX_Q9Y508
    UniProt: Q9Y508

  • Chr Location
    20q13.13; chr20:49936336-49953885 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 2 alleles in 2 genetic backgrounds
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit female infertility with reduced oocyte number and maternally influences failure of zygotic cell division.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    807
  • Tissues
    58
  • cDNA Data
    254
  • Literature Summary
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 81018 NCBI Gene Model | MGI Sequence Detail 23529 C57BL/6J ±  kb
    transcript NM_030743 RefSeq | MGI Sequence Detail 3008 C57BL/6  
    polypeptide Q9ET26 UniProt | EBI | MGI Sequence Detail 229 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 256
      cDNA 254
      Primer pair 2

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:1920985, MGI:2138866, MGI:2139384
    References
    more
    • Summaries
      All 49
      Developmental Gene Expression 6
      Gene Ontology 6
      Phenotypes 14
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory