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Nol6 Gene Detail
Summary
  • Symbol
    Nol6
  • Name
    nucleolar protein family 6 (RNA-associated)
  • Synonyms
    Nrap
  • Feature Type
    protein coding gene
  • IDs
    MGI:2140151
    NCBI Gene: 230082
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:41114427-41124450 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 20.98 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    315 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2140151
 protein coding gene Chr4:41114427-41124455 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028155
 protein coding gene Chr4:39037698-39050225 (-)
A/J MGP_AJ_G0028113
 protein coding gene Chr4:37559874-37569947 (-)
AKR/J MGP_AKRJ_G0028076
 protein coding gene Chr4:38523912-38533931 (-)
BALB/cJ MGP_BALBcJ_G0028125
 protein coding gene Chr4:37890184-37900449 (-)
C3H/HeJ MGP_C3HHeJ_G0027853
 protein coding gene Chr4:39065636-39076411 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028566
 protein coding gene Chr4:40486446-40496470 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025907
 protein coding gene Chr4:35210105-35220225 (-)
CAST/EiJ MGP_CASTEiJ_G0027309
 protein coding gene Chr4:38734023-38744946 (-)
CBA/J MGP_CBAJ_G0027825
 protein coding gene Chr4:41867336-41877397 (-)
DBA/2J MGP_DBA2J_G0027969
 protein coding gene Chr4:37480432-37490740 (-)
FVB/NJ MGP_FVBNJ_G0027936
 protein coding gene Chr4:36813060-36823094 (-)
LP/J MGP_LPJ_G0028077
 protein coding gene Chr4:39108886-39118943 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027969
 protein coding gene Chr4:45185572-45195591 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028625
 protein coding gene Chr4:38640240-38650257 (-)
PWK/PhJ MGP_PWKPhJ_G0027028
 protein coding gene Chr4:37490237-37500278 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026855
 protein coding gene Chr4:38339824-38349830 (-)
WSB/EiJ MGP_WSBEiJ_G0027385
 protein coding gene Chr4:38618124-38628133 (-)



Homology
more
  • Human Ortholog
    NOL6, nucleolar protein 6
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NOL6, nucleolar protein 6
  • Synonyms
    bA311H10.1, NRAP, UTP22
  • Links
    NCBI Gene ID: 65083
    neXtProt AC: NX_Q9H6R4
    UniProt: Q9H6R4

  • Chr Location
    9p13.3; chr9:33461353-33473930 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    736
  • Tissues
    21
  • cDNA Data
    106
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 230082 NCBI Gene Model | MGI Sequence Detail 10024 C57BL/6J ±  kb
transcript NM_139236 RefSeq | MGI Sequence Detail 4420 C57BL/6  
polypeptide Q8R5K4 UniProt | EBI | MGI Sequence Detail 1152 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 106
    cDNA 106

    Microarray probesets 4
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 8
  • Earliest
    J:76634 Utama B, et al., Isolation and characterization of a new nucleolar protein, Nrap, that is conserved from yeast to humans. Genes Cells. 2002 Feb;7(2):115-32
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory