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Tmem266 Gene Detail
Summary
  • Symbol
    Tmem266
  • Name
    transmembrane protein 266
  • Synonyms
    AI118078
  • Feature Type
    protein coding gene
  • IDs
    MGI:2142980
    NCBI Gene: 244886
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:55234197-55345629 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 29.98 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    3572 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2142980
 protein coding gene Chr9:55234194-55345629 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034841
 protein coding gene Chr9:54420206-54537623 (+)
A/J MGP_AJ_G0034822
 protein coding gene Chr9:52667546-52779229 (+)
AKR/J MGP_AKRJ_G0034751
 protein coding gene Chr9:53873311-53989517 (+)
BALB/cJ MGP_BALBcJ_G0034814
 protein coding gene Chr9:52441646-52555102 (+)
C3H/HeJ MGP_C3HHeJ_G0034524
 protein coding gene Chr9:54332913-54453672 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035333
 protein coding gene Chr9:55931528-56046977 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032245
 protein coding gene Chr9:52070111-52183030 (+)
CAST/EiJ MGP_CASTEiJ_G0033845
 protein coding gene Chr9:54369844-54484224 (+)
CBA/J MGP_CBAJ_G0034495
 protein coding gene Chr9:57887333-58003747 (+)
DBA/2J MGP_DBA2J_G0034654
 protein coding gene Chr9:52558941-52671144 (+)
FVB/NJ MGP_FVBNJ_G0034596
 protein coding gene Chr9:51761010-51876204 (+)
LP/J MGP_LPJ_G0034737
 protein coding gene Chr9:54726940-54842336 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034639
 protein coding gene Chr9:59394473-59513759 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035355
 protein coding gene Chr9:53891961-54007596 (+)
PWK/PhJ MGP_PWKPhJ_G0033550
 protein coding gene Chr9:52545212-52664452 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033385
 protein coding gene Chr9:54155640-54279757 (+)
WSB/EiJ MGP_WSBEiJ_G0033958
 protein coding gene Chr9:53847315-53966963 (+)



Homology
more
  • Human Ortholog
    TMEM266, transmembrane protein 266
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM266, transmembrane protein 266
  • Synonyms
    C15orf27, HsHVRP1, hTMEM266, HVRP1
  • Links
    NCBI Gene ID: 123591
    neXtProt AC: NX_Q2M3C6
    UniProt: Q2M3C6

  • Chr Location
    15q24.2; chr15:76059958-76229121 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit reduced stereotypic counts in open-field test.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    10
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032313 Ensembl Gene Model | MGI Sequence Detail 111433 C57BL/6J ±  kb
transcript ENSMUST00000034862 Ensembl | MGI Sequence Detail 2408 Not Applicable  
polypeptide ENSMUSP00000034862 Ensembl | MGI Sequence Detail 538 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 2
References
more
  • Summaries
    All 27
    Gene Ontology 6
    Phenotypes 6
  • Earliest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9
  • Latest
    J:325734 Kawai T, et al., Insight into the function of a unique voltage-sensor protein (TMEM266) and its short form in mouse cerebellum. Biochem J. 2022 Jun 17;479(11):1127-1145
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory