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Zfp445 Gene Detail
Summary
  • Symbol
    Zfp445
  • Name
    zinc finger protein 445
  • Synonyms
    ZNF168
  • Feature Type
    protein coding gene
  • IDs
    MGI:2143340
    NCBI Gene: 235682
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:122673594-122695071 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 73.18 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    410 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2143340
 protein coding gene Chr9:122673594-122715916 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035464
 protein coding gene Chr9:125853499-125864346 (-)
A/J MGP_AJ_G0035445
 protein coding gene Chr9:121039946-121050551 (-)
AKR/J MGP_AKRJ_G0035378
 protein coding gene Chr9:124295465-124305421 (-)
BALB/cJ MGP_BALBcJ_G0035441
 protein coding gene Chr9:120961006-120970997 (-)
C3H/HeJ MGP_C3HHeJ_G0035148
 protein coding gene Chr9:124732565-124745399 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035964
 protein coding gene Chr9:129328015-129339311 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032846
 protein coding gene Chr9:118174872-118186953 (-)
CAST/EiJ MGP_CASTEiJ_G0034453
 protein coding gene Chr9:124760001-124769852 (-)
CBA/J MGP_CBAJ_G0035116
 protein coding gene Chr9:134038461-134050038 (-)
DBA/2J MGP_DBA2J_G0035275
 protein coding gene Chr9:120489457-120499421 (-)
FVB/NJ MGP_FVBNJ_G0035222
 protein coding gene Chr9:119407718-119421171 (-)
LP/J MGP_LPJ_G0035354
 protein coding gene Chr9:126193854-126204533 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035263
 protein coding gene Chr9:134902512-134915763 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035983
 protein coding gene Chr9:124749839-124761887 (-)
PWK/PhJ MGP_PWKPhJ_G0034157
 protein coding gene Chr9:120944655-120954944 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033994
 protein coding gene Chr9:124831501-124853288 (-)
WSB/EiJ MGP_WSBEiJ_G0034573
 protein coding gene Chr9:124592443-124604754 (-)



Homology
more
  • Human Ortholog
    ZNF445, zinc finger protein 445
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF445, zinc finger protein 445
  • Synonyms
    ZFP445, ZKSCAN15, ZNF168, ZSCAN47
  • Links
    NCBI Gene ID: 353274
    neXtProt AC: NX_P59923
    UniProt: P59923

  • Chr Location
    3p21.31; chr3:44431705-44477670 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    792
  • Tissues
    77
  • cDNA Data
    239
  • Literature Summary
    8
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000047036 Ensembl Gene Model | MGI Sequence Detail 21478 C57BL/6J ±  kb
    transcript ENSMUST00000216063 Ensembl | MGI Sequence Detail 6189 Not Applicable  
    polypeptide ENSMUSP00000151198 Ensembl | MGI Sequence Detail 986 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 242
      cDNA 239
      Primer pair 2
      Other 1

      Microarray probesets 5
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 8
      Gene Ontology 5
      Phenotypes 10
    • Earliest
      J:85162 Hansen J, et al., A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory