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Aspg Gene Detail
Summary
  • Symbol
    Aspg
  • Name
    asparaginase
  • Synonyms
    A530050D06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2144822
    NCBI Gene: 104816
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:112073113-112093993 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 61.14 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    654 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2144822
 protein coding gene Chr12:112073113-112094007 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020148
 protein coding gene Chr12:114540148-114561038 (+)
A/J MGP_AJ_G0020104
 protein coding gene Chr12:110126832-110148732 (+)
AKR/J MGP_AKRJ_G0020079
 protein coding gene Chr12:113304428-113325361 (+)
BALB/cJ MGP_BALBcJ_G0020089
 protein coding gene Chr12:110557510-110578400 (+)
C3H/HeJ MGP_C3HHeJ_G0019891
 protein coding gene Chr12:113795102-113817525 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020534
 protein coding gene Chr12:118090256-118111146 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018147
 protein coding gene Chr12:106566587-106587602 (+)
CAST/EiJ MGP_CASTEiJ_G0019432
 protein coding gene Chr12:108649739-108670798 (+)
CBA/J MGP_CBAJ_G0019858
 protein coding gene Chr12:122602025-122629880 (+)
DBA/2J MGP_DBA2J_G0019975
 protein coding gene Chr12:109612520-109633609 (+)
FVB/NJ MGP_FVBNJ_G0019960
 protein coding gene Chr12:108416920-108438673 (+)
LP/J MGP_LPJ_G0020050
 protein coding gene Chr12:114363969-114384859 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019998
 protein coding gene Chr12:125710980-125731870 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020563
 protein coding gene Chr12:112816541-112839765 (+)
PWK/PhJ MGP_PWKPhJ_G0019193
 protein coding gene Chr12:104255035-104275923 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018996
 protein coding gene Chr12:106977322-106998137 (+)
WSB/EiJ MGP_WSBEiJ_G0019491
 protein coding gene Chr12:113715023-113737395 (+)



Homology
more
  • Human Ortholog
    ASPG, asparaginase
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ASPG, asparaginase
  • Synonyms
    C14orf76, GPA/WT, hASNase1, LYSOLP
  • Links
    NCBI Gene ID: 374569
    neXtProt AC: NX_Q86U10
    UniProt: Q86U10

  • Chr Location
    14q32.33
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    27
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037686 Ensembl Gene Model | MGI Sequence Detail 20881 C57BL/6J ±  kb
transcript ENSMUST00000079400 Ensembl | MGI Sequence Detail 2722 Not Applicable  
polypeptide ENSMUSP00000078369 Ensembl | MGI Sequence Detail 564 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 27
    cDNA 27

    Microarray probesets 3
Other
Accession IDs
less
MGI:2685536
References
more
  • Summaries
    All 36
    Gene Ontology 7
    Phenotypes 8
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory