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Serpinb6c Gene Detail
Summary
  • Symbol
    Serpinb6c
  • Name
    serine (or cysteine) peptidase inhibitor, clade B, member 6c
  • Synonyms
    ovalbumin, Spi3C, SPIC
  • Feature Type
    protein coding gene
  • IDs
    MGI:2145481
    NCBI Gene: 97848
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:34063799-34089691 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 13.99 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    706 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2145481
 protein coding gene Chr13:34063799-34089709 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020442
 protein coding gene Chr13:31983515-32009376 (-)
A/J MGP_AJ_G0020397
 protein coding gene Chr13:31041667-31067644 (-)
AKR/J MGP_AKRJ_G0020374
 protein coding gene Chr13:31772848-31794932 (-)
BALB/cJ MGP_BALBcJ_G0020392
 protein coding gene Chr13:31126936-31144256 (-)
C3H/HeJ MGP_C3HHeJ_G0020191
 protein coding gene Chr13:31700203-31722039 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020826
 protein coding gene Chr13:33034301-33061443 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018413
 protein coding gene Chr13:29366258-29383856 (-)
CAST/EiJ MGP_CASTEiJ_G0019707
 protein coding gene Chr13:31364504-31386864 (-)
CBA/J MGP_CBAJ_G0020151
 protein coding gene Chr13:34487282-34506535 (-)
DBA/2J MGP_DBA2J_G0020273
 protein coding gene Chr13:30565378-30591298 (-)
FVB/NJ MGP_FVBNJ_G0020253
 protein coding gene Chr13:30143929-30168236 (-)
LP/J MGP_LPJ_G0020349
 protein coding gene Chr13:32206206-32232043 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020284
 protein coding gene Chr13:34700096-34726460 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020869
 protein coding gene Chr13:31424832-31450740 (-)
PWK/PhJ MGP_PWKPhJ_G0019462
 protein coding gene Chr13:30683755-30704560 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019287
 protein coding gene Chr13:30087923-30106397 (-)
WSB/EiJ MGP_WSBEiJ_G0019769
 protein coding gene Chr13:31783720-31809460 (-)



Homology
more
  • Human Ortholog
    SERPINB6, serpin family B member 6
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SERPINB6, serpin family B member 6
  • Synonyms
    CAP, DFNB91, MSTP057, PI-6, PI6, PTI, SPI3
  • Links
    NCBI Gene ID: 5269
    neXtProt AC: NX_P35237
    UniProt: P35237

  • Chr Location
    6p25.2; chr6:2948159-2972165 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human SERPINB6 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    729
  • Tissues
    17
  • cDNA Data
    14
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000052180 Ensembl Gene Model | MGI Sequence Detail 25893 C57BL/6J ±  kb
transcript ENSMUST00000110273 Ensembl | MGI Sequence Detail 1325 Not Applicable  
polypeptide ENSMUSP00000105902 Ensembl | MGI Sequence Detail 379 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    Genomic 1
    cDNA 14
    Primer pair 3

    Microarray probesets 2
Other
Accession IDs
less
MGI:2145482
References
more
  • Summaries
    All 32
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 11
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory