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Scaf4 Gene Detail
Summary
  • Symbol
    Scaf4
  • Name
    SR-related CTD-associated factor 4
  • Synonyms
    Sfrs15, Sra4, Srsf15
  • Feature Type
    protein coding gene
  • IDs
    MGI:2146350
    NCBI Gene: 224432
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:90022568-90081391 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 51.57 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1204 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2146350
 protein coding gene Chr16:90021504-90082074 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023025
 protein coding gene Chr16:91148307-91209812 (-)
A/J MGP_AJ_G0022993
 protein coding gene Chr16:86903421-86958919 (-)
AKR/J MGP_AKRJ_G0022963
 protein coding gene Chr16:89509920-89565556 (-)
BALB/cJ MGP_BALBcJ_G0022995
 protein coding gene Chr16:87429165-87485758 (-)
C3H/HeJ MGP_C3HHeJ_G0022756
 protein coding gene Chr16:90073539-90132209 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023442
 protein coding gene Chr16:94110884-94171950 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020944
 protein coding gene Chr16:84622824-84677402 (-)
CAST/EiJ MGP_CASTEiJ_G0022275
 protein coding gene Chr16:90614684-90676282 (-)
CBA/J MGP_CBAJ_G0022725
 protein coding gene Chr16:98101538-98164534 (-)
DBA/2J MGP_DBA2J_G0022859
 protein coding gene Chr16:86808395-86863413 (-)
FVB/NJ MGP_FVBNJ_G0022833
 protein coding gene Chr16:85940457-85995414 (-)
LP/J MGP_LPJ_G0022929
 protein coding gene Chr16:90839294-90896560 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022854
 protein coding gene Chr16:102725352-102783694 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023460
 protein coding gene Chr16:90030439-90085817 (-)
PWK/PhJ MGP_PWKPhJ_G0022020
 protein coding gene Chr16:86964277-87021592 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021850
 protein coding gene Chr16:89575384-89631741 (-)
WSB/EiJ MGP_WSBEiJ_G0022327
 protein coding gene Chr16:90265142-90322417 (-)



Homology
more
  • Human Ortholog
    SCAF4, SR-related CTD associated factor 4
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SCAF4, SR-related CTD associated factor 4
  • Synonyms
    FZS, SFRS15, SRA4
  • Links
    NCBI Gene ID: 57466
    neXtProt AC: NX_O95104
    UniProt: O95104

  • Chr Location
    21q22.11; chr21:31671000-31732118 (-)  GRCh38
Human Diseases
less
  • References
    4 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    76 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    897
  • Tissues
    163
  • cDNA Data
    62
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022983 Ensembl Gene Model | MGI Sequence Detail 58824 C57BL/6J ±  kb
transcript ENSMUST00000039280 Ensembl | MGI Sequence Detail 4266 Not Applicable  
polypeptide ENSMUSP00000044472 Ensembl | MGI Sequence Detail 1209 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 65
    cDNA 62
    Primer pair 3

    Microarray probesets 5
Other
Accession IDs
less
MGI:2652143
References
more
  • Summaries
    All 104
    Developmental Gene Expression 5
    Diseases 4
    Gene Ontology 5
    Phenotypes 76
  • Earliest
    J:42265 Huang TT, et al., Superoxide-mediated cytotoxicity in superoxide dismutase-deficient fetal fibroblasts. Arch Biochem Biophys. 1997 Aug 15;344(2):424-32
  • Latest
    J:335294 Redhead Y, et al., Craniofacial dysmorphology in Down syndrome is caused by increased dosage of Dyrk1a and at least three other genes. Development. 2023 Apr 15;150(8):dev201077
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory