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Obox6 Gene Detail
Summary
  • Symbol
    Obox6
  • Name
    oocyte specific homeobox 6
  • Feature Type
    protein coding gene
  • IDs
    MGI:2149036
    NCBI Gene: 252830
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr7:15567175-15573604 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 8.59 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    198 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2149036
 protein coding gene Chr7:15567166-15573604 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031690
 protein coding gene Chr7:13456213-13461137 (-)
A/J MGP_AJ_G0031662
 protein coding gene Chr7:13285683-13291600 (-)
AKR/J MGP_AKRJ_G0031587
 protein coding gene Chr7:13583907-13590181 (-)
BALB/cJ MGP_BALBcJ_G0031669
 protein coding gene Chr7:13379282-13387081 (-)
C3H/HeJ MGP_C3HHeJ_G0031391
 protein coding gene Chr7:13748458-13752983 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032135
 protein coding gene Chr7:14216814-14222386 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029214
 protein coding gene Chr7:14855725-14860719 (-)
CAST/EiJ MGP_CASTEiJ_G0030742
 protein coding gene Chr7:10510153-10516460 (-)
CBA/J MGP_CBAJ_G0031350
 protein coding gene Chr7:14631651-14637117 (-)
DBA/2J MGP_DBA2J_G0031506
 protein coding gene Chr7:13162197-13167551 (-)
FVB/NJ MGP_FVBNJ_G0031462
 protein coding gene Chr7:13055265-13061370 (-)
LP/J MGP_LPJ_G0031591
 protein coding gene Chr7:13739663-13745334 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031497
 protein coding gene Chr7:14617235-14622842 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032164
 protein coding gene Chr7:13347736-13352604 (-)
PWK/PhJ MGP_PWKPhJ_G0030466
 protein coding gene Chr7:10675817-10683676 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030294
 protein coding gene Chr7:8278060-8282767 (-)
WSB/EiJ MGP_WSBEiJ_G0030839
 protein coding gene Chr7:13396315-13403848 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotype references
Mice homozygous for a null allele exhibit no detectable abnormal phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    796
  • Tissues
    67
  • cDNA Data
    13
  • Literature Summary
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 252830 NCBI Gene Model | MGI Sequence Detail 6430 C57BL/6J ±  kb
transcript NM_145710 RefSeq | MGI Sequence Detail 1336 C57BL/6  
polypeptide G3X9U1 UniProt | EBI | MGI Sequence Detail 347 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR050460 Distal-less homeobox transcription factors
    IPR017970 Homeobox, conserved site
    IPR001356 Homeobox domain
    IPR009057 Homeobox-like domain superfamily
Molecular
Reagents
less
  • All nucleic 15
    cDNA 13
    Primer pair 2

    Microarray probesets 3
References
more
  • Summaries
    All 30
    Developmental Gene Expression 7
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:340071 Ji S, et al., OBOX regulates mouse zygotic genome activation and early development. Nature. 2023 Aug;620(7976):1047-1053
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory