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B3galt6 Gene Detail
Summary
  • Symbol
    B3galt6
  • Name
    UDP-Gal:betaGal beta 1,3-galactosyltransferase, polypeptide 6
  • Synonyms
    GalTII
  • Feature Type
    protein coding gene
  • IDs
    MGI:2152819
    NCBI Gene: 117592
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:156073923-156077106 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 87.66 cM, cytoband E2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    273 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2152819
 protein coding gene Chr4:156073923-156077135 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029241
 protein coding gene Chr4:160355583-160358736 (-)
A/J MGP_AJ_G0029206
 protein coding gene Chr4:153599670-153602823 (-)
AKR/J MGP_AKRJ_G0029154
 protein coding gene Chr4:157777822-157780975 (-)
BALB/cJ MGP_BALBcJ_G0029222
 protein coding gene Chr4:154075516-154078669 (-)
C3H/HeJ MGP_C3HHeJ_G0028943
 protein coding gene Chr4:158340894-158344047 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029671
 protein coding gene Chr4:166041039-166044222 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026915
 protein coding gene Chr4:145877282-145880456 (-)
CAST/EiJ MGP_CASTEiJ_G0028355
 protein coding gene Chr4:155780848-155784007 (-)
CBA/J MGP_CBAJ_G0028905
 protein coding gene Chr4:171078026-171081179 (-)
DBA/2J MGP_DBA2J_G0029054
 protein coding gene Chr4:153621309-153624462 (-)
FVB/NJ MGP_FVBNJ_G0029017
 protein coding gene Chr4:152868669-152871828 (-)
LP/J MGP_LPJ_G0029144
 protein coding gene Chr4:160295552-160298735 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029044
 protein coding gene Chr4:173873567-173876726 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029703
 protein coding gene Chr4:158420287-158423440 (-)
PWK/PhJ MGP_PWKPhJ_G0028076
 protein coding gene Chr4:149760138-149763292 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027910
 protein coding gene Chr4:152673125-152676348 (-)
WSB/EiJ MGP_WSBEiJ_G0028435
 protein coding gene Chr4:158584542-158587701 (-)



Homology
more
  • Human Ortholog
    B3GALT6, beta-1,3-galactosyltransferase 6
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    B3GALT6, beta-1,3-galactosyltransferase 6
  • Synonyms
    ALGAZ, beta3GalT6, EDSP2, EDSSPD2, SEMDJL1
  • Links
    NCBI Gene ID: 126792
    neXtProt AC: NX_Q96L58
    UniProt: Q96L58

  • Chr Location
    1p36.33; chr1:1232237-1235041 (+)  GRCh38
Human Diseases
more
  • Diseases
    2 with human B3GALT6 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    802
  • Tissues
    95
  • cDNA Data
    7
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000050796 Ensembl Gene Model | MGI Sequence Detail 3184 C57BL/6J ±  kb
    transcript ENSMUST00000052185 Ensembl | MGI Sequence Detail 3184 Not Applicable  
    polypeptide ENSMUSP00000057521 Ensembl | MGI Sequence Detail 325 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 7
      Primer pair 2

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:2140636
    References
    more
    • Summaries
      All 32
      Developmental Gene Expression 3
      Gene Ontology 8
      Phenotypes 4
    • Earliest
      J:72456 Bai X, et al., Biosynthesis of the linkage region of glycosaminoglycans: cloning and activity of galactosyltransferase II, the sixth member of the beta 1,3-galactosyltransferase family (beta 3GalT6). J Biol Chem. 2001 Dec 21;276(51):48189-95
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory