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Paip1 Gene Detail
Summary
  • Symbol
    Paip1
  • Name
    polyadenylate binding protein-interacting protein 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2384993
    NCBI Gene: 218693
  • Alliance
    gene page
  • Transcription Start Sites
    12 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:119565137-119594754 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 67.22 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    750 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2384993
 protein coding gene Chr13:119564960-119596858 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020970
 protein coding gene Chr13:122446162-122481139 (+)
A/J MGP_AJ_G0020920
 protein coding gene Chr13:117481636-117519562 (+)
AKR/J MGP_AKRJ_G0020895
 protein coding gene Chr13:120961091-120994646 (+)
BALB/cJ MGP_BALBcJ_G0020920
 protein coding gene Chr13:118161740-118190709 (+)
C3H/HeJ MGP_C3HHeJ_G0020709
 protein coding gene Chr13:120777999-120810041 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021356
 protein coding gene Chr13:126022265-126051825 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018925
 protein coding gene Chr13:112471447-112499237 (+)
CAST/EiJ MGP_CASTEiJ_G0020228
 protein coding gene Chr13:120641102-120677901 (+)
CBA/J MGP_CBAJ_G0020671
 protein coding gene Chr13:130861596-130900396 (+)
DBA/2J MGP_DBA2J_G0020794
 protein coding gene Chr13:117097592-117127550 (+)
FVB/NJ MGP_FVBNJ_G0020778
 protein coding gene Chr13:115694604-115724005 (+)
LP/J MGP_LPJ_G0020870
 protein coding gene Chr13:122411607-122445980 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020806
 protein coding gene Chr13:131501289-131535264 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021392
 protein coding gene Chr13:120466043-120505274 (+)
PWK/PhJ MGP_PWKPhJ_G0019981
 protein coding gene Chr13:115982771-116013794 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019804
 protein coding gene Chr13:116844217-116876367 (+)
WSB/EiJ MGP_WSBEiJ_G0020286
 protein coding gene Chr13:121144878-121177251 (+)



Homology
more
  • Human Ortholog
    PAIP1, poly(A) binding protein interacting protein 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PAIP1, poly(A) binding protein interacting protein 1
  • Links
    NCBI Gene ID: 10605
    neXtProt AC: NX_Q9H074
    UniProt: Q9H074

  • Chr Location
    5p12; chr5:43526267-43557758 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    1
  • cDNA Data
    14
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000025451 Ensembl Gene Model | MGI Sequence Detail 29618 C57BL/6J ±  kb
    transcript ENSMUST00000126957 Ensembl | MGI Sequence Detail 1731 Not Applicable  
    polypeptide ENSMUSP00000117256 Ensembl | MGI Sequence Detail 484 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      7 Sequences
    • Protein Ontology
      PR:000012236 polyadenylate-binding protein-interacting protein 1
      (term hierarchy)
    • InterPro Domains
      IPR016024 Armadillo-type fold
      IPR009818 Ataxin-2, C-terminal
      IPR003890 MIF4G-like, type 3
      IPR051367 mRNA Translation Regulation/Replication-dependent Histone mRNA Translation
    • GlyGen
      Q8VE62 1 site, 1 N-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 15
      cDNA 14
      Primer pair 1

      Microarray probesets 8
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 2
      Gene Ontology 5
      Phenotypes 11
    • Earliest
      J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory