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Ms4a6c Gene Detail
Summary
  • Symbol
    Ms4a6c
  • Name
    membrane-spanning 4-domains, subfamily A, member 6C
  • Synonyms
    2200009H22Rik, 2210417N07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385644
    NCBI Gene: 73656
  • Member of
    Ms4ac cluster
  • Alliance
    gene page
  • Transcription Start Sites
    17 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:11446730-11459556 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 8.44 cM, cytoband B
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    435 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385644
 protein coding gene Chr19:11446718-11464433 (+)
129S1/SvImJ no annotation
A/J MGP_AJ_G0024848
 protein coding gene Chr19:8311177-8325323 (+)
AKR/J MGP_AKRJ_G0024823
 protein coding gene Chr19:8638219-8665383 (+)
BALB/cJ MGP_BALBcJ_G0024848
 protein coding gene Chr19:8328678-8343363 (+)
C3H/HeJ MGP_C3HHeJ_G0024614
 protein coding gene Chr19:8512534-8621369 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025296
 protein coding gene Chr19:9270150-9288338 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022722
 protein coding gene Chr19:8714773-8727041 (+)
CAST/EiJ MGP_CASTEiJ_G0024087
 protein coding gene Chr19:8148909-8164366 (+)
CBA/J MGP_CBAJ_G0024589
 protein coding gene Chr19:9341317-9361096 (+)
DBA/2J MGP_DBA2J_G0024715
 protein coding gene Chr19:8312851-8326462 (+)
FVB/NJ MGP_FVBNJ_G0024682
 protein coding gene Chr19:8312441-8315771 (+)
LP/J MGP_LPJ_G0024802
 protein coding gene Chr19:8821005-8836978 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024709
 protein coding gene Chr19:9228204-9240016 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025344
 protein coding gene Chr19:8630413-8644278 (+)
PWK/PhJ MGP_PWKPhJ_G0023831
 protein coding gene Chr19:7725656-7737153 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023637
 protein coding gene Chr19:7805713-7819068 (+)
WSB/EiJ MGP_WSBEiJ_G0024149
 protein coding gene Chr19:8501907-8514254 (+)



Homology
more
  • Human Ortholog
    MS4A6A, membrane spanning 4-domains A6A
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MS4A6A, membrane spanning 4-domains A6A
  • Synonyms
    4SPAN3, 4SPAN3.2, CD20L3, CDA01, MS4A6, MST090, MSTP090
  • Links
    NCBI Gene ID: 64231
    neXtProt AC: NX_Q9H2W1
    UniProt: Q9H2W1

  • Chr Location
    11q12.2; chr11:60171607-60184666 (-)  GRCh38
  • Human Ortholog
    MS4A6E, membrane spanning 4-domains A6E
  • Links
    NCBI Gene ID: 245802
    neXtProt AC: NX_Q96DS6
    UniProt: Q96DS6

  • Chr Location
    11q12.2; chr11:60327255-60396596 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    730
  • Tissues
    15
  • cDNA Data
    10
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000079419 Ensembl Gene Model | MGI Sequence Detail 12827 C57BL/6J ±  kb
transcript ENSMUST00000165310 Ensembl | MGI Sequence Detail 1841 Not Applicable  
polypeptide ENSMUSP00000132425 Ensembl | MGI Sequence Detail 217 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 3
Other
Accession IDs
less
MGI:1920906, MGI:1925737
References
more
  • Summaries
    All 27
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory