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Paip2b Gene Detail
Summary
  • Symbol
    Paip2b
  • Name
    poly(A) binding protein interacting protein 2B
  • Synonyms
    MGC:27648, MGC:49717
  • Feature Type
    protein coding gene
  • IDs
    MGI:2386865
    NCBI Gene: 232164
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:83783040-83808723 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 35.97 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    499 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2386865
 protein coding gene Chr6:83782383-83808723 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030942
 protein coding gene Chr6:84841133-84869000 (-)
A/J MGP_AJ_G0030911
 protein coding gene Chr6:81610536-81636986 (-)
AKR/J MGP_AKRJ_G0030839
 protein coding gene Chr6:83971344-83997581 (-)
BALB/cJ MGP_BALBcJ_G0030921
 protein coding gene Chr6:81638604-81665784 (-)
C3H/HeJ MGP_C3HHeJ_G0030789
 protein coding gene Chr6:100410288-100435545 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031381
 protein coding gene Chr6:87186948-87213428 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028567
 protein coding gene Chr6:79974812-80003580 (-)
CAST/EiJ MGP_CASTEiJ_G0030030
 protein coding gene Chr6:83999074-84025190 (-)
CBA/J MGP_CBAJ_G0030608
 protein coding gene Chr6:90609691-90636290 (-)
DBA/2J MGP_DBA2J_G0030761
 protein coding gene Chr6:80923768-80950271 (-)
FVB/NJ MGP_FVBNJ_G0030714
 protein coding gene Chr6:80135903-80162409 (-)
LP/J MGP_LPJ_G0030840
 protein coding gene Chr6:84846901-84873799 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030750
 protein coding gene Chr6:94869163-94897620 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031405
 protein coding gene Chr6:83802313-83830962 (-)
PWK/PhJ MGP_PWKPhJ_G0029745
 protein coding gene Chr6:79843572-79866714 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029573
 protein coding gene Chr6:82625301-82651587 (-)
WSB/EiJ MGP_WSBEiJ_G0030111
 protein coding gene Chr6:84223880-84248258 (-)



Homology
more
  • Human Ortholog
    PAIP2B, poly(A) binding protein interacting protein 2B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PAIP2B, poly(A) binding protein interacting protein 2B
  • Links
    NCBI Gene ID: 400961
    neXtProt AC: NX_Q9ULR5
    UniProt: Q9ULR5

  • Chr Location
    2p13.3; chr2:71182738-71227103 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    14 phenotypes from multigenic genotypes
    15 phenotype references
Mice homozygous for a knock-out allele exhibit normal reproductive system physiology.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    707
  • Tissues
    1
  • cDNA Data
    203
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 232164 NCBI Gene Model | MGI Sequence Detail 25684 C57BL/6J ±  kb
transcript NM_146169 RefSeq | MGI Sequence Detail 3330 C57BL/6  
polypeptide Q91W45 UniProt | EBI | MGI Sequence Detail 136 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000012238 polyadenylate-binding protein-interacting protein 2B
    (term hierarchy)
  • InterPro Domains
    IPR009818 Ataxin-2, C-terminal
    IPR040396 Polyadenylate-binding protein-interacting protein 2-like
Molecular
Reagents
less
  • All nucleic 203
    cDNA 203

    Microarray probesets 3
References
more
  • Summaries
    All 38
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 15
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:330636 Iwata S, et al., An efficient i-GONAD method for creating and maintaining lethal mutant mice using an inversion balancer identified from the C3H/HeJJcl strain. G3 (Bethesda). 2021;11(8)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory