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Lrrc66 Gene Detail
Summary
  • Symbol
    Lrrc66
  • Name
    leucine rich repeat containing 66
  • Synonyms
    MGC:38937
  • Feature Type
    protein coding gene
  • IDs
    MGI:2387634
    NCBI Gene: 231296
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:73763985-73789771 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 5, 38.89 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    848 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2387634
protein coding gene Chr5:73763985-73789869 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029627
protein coding gene Chr5:73620822-73646707 (-)
A/J MGP_AJ_G0029595
protein coding gene Chr5:70856627-70882458 (-)
AKR/J MGP_AKRJ_G0029543
protein coding gene Chr5:73160273-73186086 (-)
BALB/cJ MGP_BALBcJ_G0029604
protein coding gene Chr5:71569063-71594897 (-)
C3H/HeJ MGP_C3HHeJ_G0029327
protein coding gene Chr5:73554709-73582781 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030058
protein coding gene Chr5:76655452-76681655 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027298
protein coding gene Chr5:66535666-66561355 (-)
CAST/EiJ MGP_CASTEiJ_G0028735
protein coding gene Chr5:72624328-72651618 (-)
CBA/J MGP_CBAJ_G0029296
protein coding gene Chr5:79166821-79193015 (-)
DBA/2J MGP_DBA2J_G0029441
protein coding gene Chr5:70939437-70965448 (-)
FVB/NJ MGP_FVBNJ_G0029402
protein coding gene Chr5:70081715-70107527 (-)
LP/J MGP_LPJ_G0029527
protein coding gene Chr5:74064758-74090670 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029429
protein coding gene Chr5:82439678-82465666 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030091
protein coding gene Chr5:72694646-72720472 (-)
PWK/PhJ MGP_PWKPhJ_G0028458
protein coding gene Chr5:69907694-69933962 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028293
protein coding gene Chr5:72045866-72071880 (-)
WSB/EiJ MGP_WSBEiJ_G0028815
protein coding gene Chr5:72997226-73023074 (-)



Homology
more
  • Human Ortholog
    LRRC66, leucine rich repeat containing 66
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LRRC66, leucine rich repeat containing 66
  • Links
    NCBI Gene ID: 339977
    neXtProt AC: NX_Q68CR7
    UniProt: Q68CR7

  • Chr Location
    4q12; chr4:51993652-52020363 (-)  GRCh38

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    358 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

Biological Process

Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 231296 NCBI Gene Model | MGI Sequence Detail 25787 C57BL/6J ±  kb
transcript NM_153568 RefSeq | MGI Sequence Detail 3100 C57BL/6  
polypeptide Q8K0B3 UniProt | EBI | MGI Sequence Detail 872 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 2
References
more
  • Summaries
    All 375
    Diseases 1
    Gene Ontology 1
    Phenotypes 358
  • Earliest
    J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
  • Latest
    J:353367 Taketomi Y, et al., Lipid-orchestrated paracrine circuit coordinates mast cell maturation and anaphylaxis through functional interaction with fibroblasts. Immunity. 2024 Aug 13;57(8):1828-1847.e11

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/05/2024
MGI 6.24
The Jackson Laboratory