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Gldn Gene Detail
Summary
  • Symbol
    Gldn
  • Name
    gliomedin
  • Synonyms
    CRG-L2, Crlg2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2388361
    NCBI Gene: 235379
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:54193770-54249061 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 29.52 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1656 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2388361
 protein coding gene Chr9:54193770-54249070 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034822
 protein coding gene Chr9:53331232-53382125 (+)
A/J MGP_AJ_G0034803
 protein coding gene Chr9:51630668-51682295 (+)
AKR/J MGP_AKRJ_G0034731
 protein coding gene Chr9:52786671-52846047 (+)
BALB/cJ MGP_BALBcJ_G0034795
 protein coding gene Chr9:51398180-51453663 (+)
C3H/HeJ MGP_C3HHeJ_G0034505
 protein coding gene Chr9:53263391-53314233 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035314
 protein coding gene Chr9:54823008-54873224 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032226
 protein coding gene Chr9:51042222-51093126 (+)
CAST/EiJ MGP_CASTEiJ_G0033827
 protein coding gene Chr9:53276001-53328499 (+)
CBA/J MGP_CBAJ_G0034476
 protein coding gene Chr9:56695802-56758165 (+)
DBA/2J MGP_DBA2J_G0034635
 protein coding gene Chr9:51516786-51572165 (+)
FVB/NJ MGP_FVBNJ_G0034577
 protein coding gene Chr9:50713978-50765088 (+)
LP/J MGP_LPJ_G0034717
 protein coding gene Chr9:53635369-53691146 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034620
 protein coding gene Chr9:58275262-58331461 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035336
 protein coding gene Chr9:52790470-52848411 (+)
PWK/PhJ MGP_PWKPhJ_G0033531
 protein coding gene Chr9:51491277-51542941 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033366
 protein coding gene Chr9:53070217-53123379 (+)
WSB/EiJ MGP_WSBEiJ_G0033939
 protein coding gene Chr9:52774456-52826005 (+)



Homology
more
  • Human Ortholog
    GLDN, gliomedin
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GLDN, gliomedin
  • Synonyms
    CLOM, COLM, CRG-L2, CRGL2, LCCS11, UNC-112, UNC-122
  • Links
    NCBI Gene ID: 342035
    neXtProt AC: NX_Q6ZMI3
    UniProt: Q6ZMI3

  • Chr Location
    15q21.2; chr15:51341655-51413365 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human GLDN associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    4 phenotypes from multigenic genotypes
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele fail to form heminodes without overt neurological abnormalities or alteration in nerve conduction.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    719
  • Tissues
    12
  • cDNA Data
    5
  • Literature Summary
    4
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 235379 NCBI Gene Model | MGI Sequence Detail 55292 C57BL/6J ±  kb
transcript NM_177350 RefSeq | MGI Sequence Detail 4649 C57BL/6  
polypeptide Q8BMF8 UniProt | EBI | MGI Sequence Detail 549 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 5
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 30
    Developmental Gene Expression 4
    Gene Ontology 9
    Phenotypes 7
  • Earliest
    J:86019 Graveel CR, et al., Identification and characterization of CRG-L2, a new marker for liver tumor development. Oncogene. 2003 Mar 20;22(11):1730-6
  • Latest
    J:327415 Jing J, et al., Spatiotemporal single-cell regulatory atlas reveals neural crest lineage diversification and cellular function during tooth morphogenesis. Nat Commun. 2022 Aug 16;13(1):4803
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory