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Muc15 Gene Detail
Summary
  • Symbol
    Muc15
  • Name
    mucin 15
  • Synonyms
    D730046L02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442110
    NCBI Gene: 269328
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:110551839-110569882 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 2, 56.75 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    683 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442110
protein coding gene Chr2:110551685-110569882 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026248
protein coding gene Chr2:113080465-113099331 (+)
A/J MGP_AJ_G0026209
protein coding gene Chr2:108359397-108377973 (+)
AKR/J MGP_AKRJ_G0026189
protein coding gene Chr2:111407824-111428107 (+)
BALB/cJ MGP_BALBcJ_G0026219
protein coding gene Chr2:108655803-108673903 (+)
C3H/HeJ MGP_C3HHeJ_G0025968
protein coding gene Chr2:111679365-111701730 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026670
protein coding gene Chr2:116772870-116795601 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024055
protein coding gene Chr2:103848936-103865972 (+)
CAST/EiJ MGP_CASTEiJ_G0025433
protein coding gene Chr2:112169417-112188708 (+)
CBA/J MGP_CBAJ_G0025946
protein coding gene Chr2:120776985-120800511 (+)
DBA/2J MGP_DBA2J_G0026084
protein coding gene Chr2:107852282-107870846 (+)
FVB/NJ MGP_FVBNJ_G0026047
protein coding gene Chr2:106770312-106789298 (+)
LP/J MGP_LPJ_G0026187
protein coding gene Chr2:113269640-113289085 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026071
protein coding gene Chr2:124970128-125009102 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026723
protein coding gene Chr2:111566951-111591793 (+)
PWK/PhJ MGP_PWKPhJ_G0025168
protein coding gene Chr2:107466224-107484732 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024968
protein coding gene Chr2:110814569-110832130 (+)
WSB/EiJ MGP_WSBEiJ_G0025500
protein coding gene Chr2:112318394-112338144 (+)



Homology
more
  • Human Ortholog
    MUC15, mucin 15, cell surface associated
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MUC15, mucin 15, cell surface associated
  • Synonyms
    MUC-15, PAS3, PASIII
  • Links
    NCBI Gene ID: 143662
    neXtProt AC: NX_Q8N387
    UniProt: Q8N387

  • Chr Location
    11p14.2; chr11:26559032-26572263 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 269328 NCBI Gene Model | MGI Sequence Detail 18044 C57BL/6J ±  kb
transcript NM_172979 RefSeq | MGI Sequence Detail 3277 C57BL/6  
polypeptide Q8C6Z1 UniProt | EBI | MGI Sequence Detail 331 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 124
    cDNA 124

    Microarray probesets 3
References
more
  • Summaries
    All 30
    Developmental Gene Expression 2
    Gene Ontology 1
    Phenotypes 9
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:321793 Han T, et al., Downregulation of MUC15 by miR-183-5p.1 promotes liver tumor-initiating cells properties and tumorigenesis via regulating c-MET/PI3K/AKT/SOX2 axis. Cell Death Dis. 2022 Mar 2;13(3):200

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory