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Map9 Gene Detail
Summary
  • Symbol
    Map9
  • Name
    microtubule-associated protein 9
  • Synonyms
    5033421J10Rik, 5330427D05Rik, ASAP, Mtap9
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442208
    NCBI Gene: 213582
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:82265379-82302575 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 36.37 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1453 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442208
 protein coding gene Chr3:82265351-82302575 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027327
 protein coding gene Chr3:82163248-82203429 (+)
A/J MGP_AJ_G0027289
 protein coding gene Chr3:79454317-79491661 (+)
AKR/J MGP_AKRJ_G0027257
 protein coding gene Chr3:81332754-81372029 (+)
BALB/cJ MGP_BALBcJ_G0027300
 protein coding gene Chr3:79546457-79582311 (+)
C3H/HeJ MGP_C3HHeJ_G0027044
 protein coding gene Chr3:81615465-81651976 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027746
 protein coding gene Chr3:85267489-85310832 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025099
 protein coding gene Chr3:75208846-75245949 (+)
CAST/EiJ MGP_CASTEiJ_G0026491
 protein coding gene Chr3:81808214-81844536 (+)
CBA/J MGP_CBAJ_G0027019
 protein coding gene Chr3:88141140-88179280 (+)
DBA/2J MGP_DBA2J_G0027155
 protein coding gene Chr3:79006362-79041736 (+)
FVB/NJ MGP_FVBNJ_G0027123
 protein coding gene Chr3:77294129-77329167 (+)
LP/J MGP_LPJ_G0027263
 protein coding gene Chr3:83159132-83197886 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027142
 protein coding gene Chr3:94516133-94554186 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027804
 protein coding gene Chr3:81135630-81174197 (+)
PWK/PhJ MGP_PWKPhJ_G0026225
 protein coding gene Chr3:78744786-78782393 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026041
 protein coding gene Chr3:80326746-80401002 (+)
WSB/EiJ MGP_WSBEiJ_G0026569
 protein coding gene Chr3:81474233-81511484 (+)



Homology
more
  • Human Ortholog
    MAP9, microtubule associated protein 9
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MAP9, microtubule associated protein 9
  • Synonyms
    ASAP
  • Links
    NCBI Gene ID: 79884
    neXtProt AC: NX_Q49MG5
    UniProt: Q49MG5

  • Chr Location
    4q32.1; chr4:155342658-155376970 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 2 alleles in 2 genetic backgrounds
    3 phenotypes from multigenic genotypes
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous or heterozygous for a null allele exhibit increased aneuploidy, chromosomal instability, detached centrosomes and pericentriolar material fragmentation in MEFs.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    26
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    56
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 213582 NCBI Gene Model | MGI Sequence Detail 37197 C57BL/6J ±  kb
    transcript NM_001081230 RefSeq | MGI Sequence Detail 6218 Not Specified  
    polypeptide Q3TRR0 UniProt | EBI | MGI Sequence Detail 646 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 56
      cDNA 56

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1923244
    References
    more
    • Summaries
      All 34
      Diseases 1
      Gene Ontology 6
      Phenotypes 10
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:299895 Wang S, et al., MAP9 Loss Triggers Chromosomal Instability, Initiates Colorectal Tumorigenesis, and Is Associated with Poor Survival of Patients with Colorectal Cancer. Clin Cancer Res. 2020 Feb 1;26(3):746-757
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory