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Amz1 Gene Detail
Summary
  • Symbol
    Amz1
  • Name
    archaelysin family metallopeptidase 1
  • Synonyms
    6530401C20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442258
    NCBI Gene: 231842
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:140709882-140739067 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 79.27 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    890 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442258
 protein coding gene Chr5:140709882-140747194 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030306
 protein coding gene Chr5:145840271-145887770 (+)
A/J MGP_AJ_G0030275
 protein coding gene Chr5:139609175-139649349 (+)
AKR/J MGP_AKRJ_G0030207
 protein coding gene Chr5:143970719-144011975 (+)
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0030737
 protein coding gene Chr5:151232302-151279758 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027955
 protein coding gene Chr5:133441252-133478176 (+)
CAST/EiJ MGP_CASTEiJ_G0029408
 protein coding gene Chr5:144199543-144241465 (+)
CBA/J MGP_CBAJ_G0029973
 protein coding gene Chr5:157422741-157466004 (+)
DBA/2J MGP_DBA2J_G0030123
 protein coding gene Chr5:139422343-139460242 (+)
FVB/NJ MGP_FVBNJ_G0030078
 protein coding gene Chr5:138578133-138616829 (+)
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0030109
 protein coding gene Chr5:160018140-160062389 (+)
NZO/HlLtJ no annotation
PWK/PhJ MGP_PWKPhJ_G0029123
 protein coding gene Chr5:138445901-138486220 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028959
 protein coding gene Chr5:141519921-141560205 (+)
WSB/EiJ MGP_WSBEiJ_G0029482
 protein coding gene Chr5:144601393-144650018 (+)



Homology
more
  • Human Ortholog
    AMZ1, archaelysin family metallopeptidase 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    AMZ1, archaelysin family metallopeptidase 1
  • Links
    NCBI Gene ID: 155185
    neXtProt AC: NX_Q400G9
    UniProt: Q400G9

  • Chr Location
    7p22.3; chr7:2679522-2775500 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    10
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 231842 NCBI Gene Model | MGI Sequence Detail 29186 C57BL/6J ±  kb
transcript NM_173405 RefSeq | MGI Sequence Detail 2685 C57BL/6  
polypeptide Q8BVF9 UniProt | EBI | MGI Sequence Detail 502 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 3
References
more
  • Summaries
    All 22
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory