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Ust Gene Detail
Summary
  • Symbol
    Ust
  • Name
    uronyl-2-sulfotransferase
  • Synonyms
    D930010O20Rik, UA2OST
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442406
    NCBI Gene: 338362
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:8080520-8394589 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 2.65 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    9317 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442406
 protein coding gene Chr10:8068499-8394701 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017003
 protein coding gene Chr10:5467408-5795854 (-)
A/J MGP_AJ_G0016981
 protein coding gene Chr10:5192983-5501468 (-)
AKR/J MGP_AKRJ_G0016945
 protein coding gene Chr10:5295226-5587743 (-)
BALB/cJ MGP_BALBcJ_G0016939
 protein coding gene Chr10:5162787-5451158 (-)
C3H/HeJ MGP_C3HHeJ_G0016764
 protein coding gene Chr10:5441147-5769972 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017401
 protein coding gene Chr10:5594447-5920262 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015106
 protein coding gene Chr10:4762372-5056179 (-)
CAST/EiJ MGP_CASTEiJ_G0016346
 protein coding gene Chr10:5351337-5662227 (-)
CBA/J MGP_CBAJ_G0016736
 protein coding gene Chr10:5789642-6121651 (-)
DBA/2J MGP_DBA2J_G0016844
 protein coding gene Chr10:5119525-5423304 (-)
FVB/NJ MGP_FVBNJ_G0016839
 protein coding gene Chr10:5063489-5372808 (-)
LP/J MGP_LPJ_G0016919
 protein coding gene Chr10:5290273-5614986 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016869
 protein coding gene Chr10:5704723-6035555 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017439
 protein coding gene Chr10:5252787-5567559 (-)
PWK/PhJ MGP_PWKPhJ_G0016131
 protein coding gene Chr10:5088023-5386680 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015913
 protein coding gene Chr10:5327451-5648104 (-)
WSB/EiJ MGP_WSBEiJ_G0016408
 protein coding gene Chr10:5257982-5581009 (-)



Homology
more
  • Human Ortholog
    UST, uronyl 2-sulfotransferase
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    UST, uronyl 2-sulfotransferase
  • Synonyms
    2OST
  • Links
    NCBI Gene ID: 10090
    neXtProt AC: NX_Q9Y2C2
    UniProt: Q9Y2C2

  • Chr Location
    6q25.1; chr6:148747030-149076990 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human UST associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    821
  • Tissues
    105
  • cDNA Data
    15
  • Literature Summary
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000047712 Ensembl Gene Model | MGI Sequence Detail 314070 C57BL/6J ±  kb
transcript ENSMUST00000061601 Ensembl | MGI Sequence Detail 4228 Not Applicable  
polypeptide ENSMUSP00000052017 Ensembl | MGI Sequence Detail 407 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    cDNA 15
    Primer pair 2

    Microarray probesets 3
References
more
  • Summaries
    All 34
    Developmental Gene Expression 7
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory