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Vash1 Gene Detail
Summary
  • Symbol
    Vash1
  • Name
    vasohibin 1
  • Synonyms
    D930046M13Rik, G630009D10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442543
    NCBI Gene: 238328
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:86725474-86738865 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 40.84 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    475 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442543
 protein coding gene Chr12:86725474-86742462 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019971
 protein coding gene Chr12:87537889-87552825 (+)
A/J MGP_AJ_G0019928
 protein coding gene Chr12:84206454-84219851 (+)
AKR/J MGP_AKRJ_G0019904
 protein coding gene Chr12:86492472-86505792 (+)
BALB/cJ MGP_BALBcJ_G0019908
 protein coding gene Chr12:84548413-84562174 (+)
C3H/HeJ MGP_C3HHeJ_G0019714
 protein coding gene Chr12:86970565-86985321 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020359
 protein coding gene Chr12:90051804-90065184 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017977
 protein coding gene Chr12:81092163-81105543 (+)
CAST/EiJ MGP_CASTEiJ_G0019264
 protein coding gene Chr12:81974944-81988222 (+)
CBA/J MGP_CBAJ_G0019685
 protein coding gene Chr12:93514726-93528004 (+)
DBA/2J MGP_DBA2J_G0019799
 protein coding gene Chr12:83709138-83722631 (+)
FVB/NJ MGP_FVBNJ_G0019786
 protein coding gene Chr12:82689640-82703199 (+)
LP/J MGP_LPJ_G0019873
 protein coding gene Chr12:87409889-87424533 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019825
 protein coding gene Chr12:96278718-96292056 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020392
 protein coding gene Chr12:86116344-86131234 (+)
PWK/PhJ MGP_PWKPhJ_G0019027
 protein coding gene Chr12:78254956-78269773 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018823
 protein coding gene Chr12:80608675-80623488 (+)
WSB/EiJ MGP_WSBEiJ_G0019316
 protein coding gene Chr12:86858250-86872456 (+)



Homology
more
  • Human Ortholog
    VASH1, vasohibin 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    VASH1, vasohibin 1
  • Synonyms
    KIAA1036, TTCP 1
  • Links
    NCBI Gene ID: 22846
    neXtProt AC: NX_Q7L8A9
    UniProt: Q7L8A9

  • Chr Location
    14q24.3; chr14:76761468-76783015 (+)  GRCh38
Human Diseases
more
  • Diseases
    2 with human VASH1 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    1
  • Targeted
    3
  • Transgenic
    1
  • Genomic Mutations
    1 involving Vash1
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    20 strains or lines available
Homozygous null mice have defects in terminating angiogenesis that occurs near wounds.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    32
  • GO References
    13
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    773
  • Tissues
    20
  • cDNA Data
    38
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021256 Ensembl Gene Model | MGI Sequence Detail 13392 C57BL/6J ±  kb
transcript ENSMUST00000021681 Ensembl | MGI Sequence Detail 2599 Not Applicable  
polypeptide ENSMUSP00000021681 Ensembl | MGI Sequence Detail 375 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 40
    cDNA 39
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2144886
References
more
  • Summaries
    All 52
    Developmental Gene Expression 4
    Gene Ontology 13
    Phenotypes 17
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory