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Lrrc49 Gene Detail
Summary
  • Symbol
    Lrrc49
  • Name
    leucine rich repeat containing 49
  • Synonyms
    D430025H09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442689
    NCBI Gene: 102747
  • Alliance
    gene page
  • Transcription Start Sites
    15 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:60494507-60595460 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 32.75 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2788 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442689
 protein coding gene Chr9:60476142-60595460 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034910
 protein coding gene Chr9:59988094-60110509 (-)
A/J MGP_AJ_G0034890
 protein coding gene Chr9:58053867-58173618 (-)
AKR/J MGP_AKRJ_G0034820
 protein coding gene Chr9:59400035-59523433 (-)
BALB/cJ MGP_BALBcJ_G0034883
 protein coding gene Chr9:57769679-57893221 (-)
C3H/HeJ MGP_C3HHeJ_G0034593
 protein coding gene Chr9:59875385-60007476 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035402
 protein coding gene Chr9:61633431-61759447 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032313
 protein coding gene Chr9:57763032-57874819 (-)
CAST/EiJ MGP_CASTEiJ_G0033914
 protein coding gene Chr9:59986631-60106195 (-)
CBA/J MGP_CBAJ_G0034564
 protein coding gene Chr9:63794306-63914937 (-)
DBA/2J MGP_DBA2J_G0034723
 protein coding gene Chr9:57853740-57979367 (-)
FVB/NJ MGP_FVBNJ_G0034665
 protein coding gene Chr9:57127103-57249800 (-)
LP/J MGP_LPJ_G0034806
 protein coding gene Chr9:60279667-60414429 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034708
 protein coding gene Chr9:65244939-65383139 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035424
 protein coding gene Chr9:59418772-59545241 (-)
PWK/PhJ MGP_PWKPhJ_G0033618
 protein coding gene Chr9:57943720-58067343 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033451
 protein coding gene Chr9:59695274-59829040 (-)
WSB/EiJ MGP_WSBEiJ_G0034027
 protein coding gene Chr9:59352319-59480774 (-)



Homology
more
  • Human Ortholog
    LRRC49, leucine rich repeat containing 49
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LRRC49, leucine rich repeat containing 49
  • Synonyms
    CSTPP2, PGs4
  • Links
    NCBI Gene ID: 54839
    neXtProt AC: NX_Q8IUZ0
    UniProt: Q8IUZ0

  • Chr Location
    15q23; chr15:70853239-71053658 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    759
  • Tissues
    44
  • cDNA Data
    68
  • Literature Summary
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 102747 NCBI Gene Model | MGI Sequence Detail 100954 C57BL/6J ±  kb
transcript NM_145616 RefSeq | MGI Sequence Detail 3000 C57BL/6  
polypeptide Q91YK0 UniProt | EBI | MGI Sequence Detail 686 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 69
    cDNA 69

    Microarray probesets 6
Other
Accession IDs
less
MGI:2143047, MGI:2143284
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory