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Katnip Gene Detail
Summary
  • Symbol
    Katnip
  • Name
    katanin interacting protein
  • Synonyms
    D430042O09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442760
    NCBI Gene: 233865
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:125307060-125473965 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 69.01 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    3545 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442760
 protein coding gene Chr7:125307027-125473967 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032971
 protein coding gene Chr7:129927295-130100749 (+)
A/J MGP_AJ_G0032954
 protein coding gene Chr7:126520641-126690523 (+)
AKR/J MGP_AKRJ_G0032886
 protein coding gene Chr7:129716370-129884209 (+)
BALB/cJ MGP_BALBcJ_G0032959
 protein coding gene Chr7:126177203-126343924 (+)
C3H/HeJ MGP_C3HHeJ_G0032669
 protein coding gene Chr7:129640862-129807080 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033465
 protein coding gene Chr7:135006512-135180382 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030437
 protein coding gene Chr7:127720918-127890840 (+)
CAST/EiJ MGP_CASTEiJ_G0031997
 protein coding gene Chr7:121430765-121645551 (+)
CBA/J MGP_CBAJ_G0032642
 protein coding gene Chr7:139543551-139715882 (+)
DBA/2J MGP_DBA2J_G0032794
 protein coding gene Chr7:124499046-124666054 (+)
FVB/NJ MGP_FVBNJ_G0032747
 protein coding gene Chr7:124334296-124508807 (+)
LP/J MGP_LPJ_G0032888
 protein coding gene Chr7:131395730-131567087 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032779
 protein coding gene Chr7:140776029-140948035 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033485
 protein coding gene Chr7:128718531-128888020 (+)
PWK/PhJ MGP_PWKPhJ_G0031705
 protein coding gene Chr7:117478537-117688127 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031551
 protein coding gene Chr7:115538832-115711800 (+)
WSB/EiJ MGP_WSBEiJ_G0032110
 protein coding gene Chr7:129689009-129862153 (+)



Homology
more
  • Human Ortholog
    KATNIP, katanin interacting protein
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KATNIP, katanin interacting protein
  • Synonyms
    JBTS26, KIAA0556
  • Links
    NCBI Gene ID: 23247
    neXtProt AC: NX_O60303
    UniProt: O60303

  • Chr Location
    16p12.1; chr16:27550133-27780344 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with Katnip mouse models; 1 with human KATNIP associations

Human Disease Mouse Models
      
IDs
 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotypes from 2 alleles in 2 genetic backgrounds
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trapped allele exhibit variable obstructive hydrocephaly and enlarged lateral ventricles resulting from a blockage of cerebrospinal fluid flow in the cerebral aqueduct but show no gross defects in ventricular ependymal cilium structure or motility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    717
  • Tissues
    5
  • cDNA Data
    44
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000032743 Ensembl Gene Model | MGI Sequence Detail 166906 C57BL/6J ±  kb
    transcript ENSMUST00000069660 Ensembl | MGI Sequence Detail 6148 Not Applicable  
    polypeptide ENSMUSP00000065744 Ensembl | MGI Sequence Detail 1610 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 45
      cDNA 45

      Microarray probesets 11
    Other
    Accession IDs
    less
    MGI:6449852
    References
    more
    • Summaries
      All 29
      Developmental Gene Expression 1
      Diseases 1
      Gene Ontology 4
      Phenotypes 8
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory