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Ifi208 Gene Detail
Summary
  • Symbol
    Ifi208
  • Name
    interferon activated gene 208
  • Synonyms
    E430029J22Rik, Pydc3, Pyr-rv1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442822
    NCBI Gene: 100033459
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:173501241-173525961 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 1, 80.57 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1084 from dbSNP Build 142
  • Strain Annotations
    12
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442822
protein coding gene Chr1:173501194-173525961 (+)
129S1/SvImJ no annotation
A/J MGP_AJ_G0016789
protein coding gene Chr1:172063416-172078297 (-)
AKR/J MGP_AKRJ_G0016757
protein coding gene Chr1:177531765-177576823 (+)
BALB/cJ MGP_BALBcJ_G0016750
protein coding gene Chr1:172898568-172916943 (+)
C3H/HeJ MGP_C3HHeJ_G0016574
protein coding gene Chr1:178161739-178205281 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017212
protein coding gene Chr1:185422075-185567291 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014917
protein coding gene Chr1:163925757-163937238 (-)
CAST/EiJ MGP_CASTEiJ_G0016152
protein coding gene Chr1:177224766-177233961 (-)
CBA/J no annotation
DBA/2J MGP_DBA2J_G0016655
protein coding gene Chr1:171286888-171345720 (+)
FVB/NJ no annotation
LP/J MGP_LPJ_G0016724
protein coding gene Chr1:180619401-180629012 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016677
protein coding gene Chr1:199221581-199253588 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017247
protein coding gene Chr1:177194275-177201180 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    IFI16, interferon gamma inducible protein 16
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IFI16, interferon gamma inducible protein 16
  • Synonyms
    IFNGIP1, PYHIN2
  • Links
    NCBI Gene ID: 3428
    neXtProt AC: NX_Q16666
    UniProt: Q16666

  • Chr Location
    1q23.1; chr1:158999968-159055155 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    2 phenotypes from multigenic genotypes
    80 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000066677 Ensembl Gene Model | MGI Sequence Detail 24721 C57BL/6J ±  kb
    transcript ENSMUST00000085876 Ensembl | MGI Sequence Detail 2990 Not Applicable  
    polypeptide ENSMUSP00000083039 Ensembl | MGI Sequence Detail 588 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 9

      Microarray probesets 1
    Other
    Accession IDs
    less
    MGI:3796068
    References
    more
    • Summaries
      All 99
      Gene Ontology 3
      Phenotypes 80
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:347111 Zhang M, et al., ITPR2 Mediated Calcium Homeostasis in Oligodendrocytes is Essential for Myelination and Involved in Depressive-Like Behavior in Adolescent Mice. Adv Sci (Weinh). 2024 Mar 13;:e2306498

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    12/10/2024
    MGI 6.24
    The Jackson Laboratory