About   Help   FAQ
Zfp574 Gene Detail
Summary
  • Symbol
    Zfp574
  • Name
    zinc finger protein 574
  • Synonyms
    A630056B21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442951
    NCBI Gene: 232976
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:24775099-24782917 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 13.73 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    236 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442951
 protein coding gene Chr7:24771992-24782917 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031853
 protein coding gene Chr7:23499302-23510226 (+)
A/J MGP_AJ_G0031832
 protein coding gene Chr7:22912057-22922983 (+)
AKR/J MGP_AKRJ_G0031761
 protein coding gene Chr7:23447272-23458198 (+)
BALB/cJ MGP_BALBcJ_G0031839
 protein coding gene Chr7:23116845-23127764 (+)
C3H/HeJ MGP_C3HHeJ_G0031558
 protein coding gene Chr7:23872257-23883174 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032301
 protein coding gene Chr7:24285690-24296859 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029356
 protein coding gene Chr7:24339333-24350913 (+)
CAST/EiJ MGP_CASTEiJ_G0030898
 protein coding gene Chr7:17345057-17357439 (+)
CBA/J MGP_CBAJ_G0031523
 protein coding gene Chr7:25176641-25187619 (+)
DBA/2J MGP_DBA2J_G0031677
 protein coding gene Chr7:22816331-22827256 (+)
FVB/NJ MGP_FVBNJ_G0031630
 protein coding gene Chr7:22805802-22816727 (+)
LP/J MGP_LPJ_G0031756
 protein coding gene Chr7:23810974-23821888 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031667
 protein coding gene Chr7:24906649-24917579 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032333
 protein coding gene Chr7:23146774-23159103 (+)
PWK/PhJ MGP_PWKPhJ_G0030622
 protein coding gene Chr7:17746105-17757083 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030453
 protein coding gene Chr7:14460869-14471675 (+)
WSB/EiJ MGP_WSBEiJ_G0031001
 protein coding gene Chr7:23317529-23328453 (+)



Homology
more
  • Human Ortholog
    ZNF574, zinc finger protein 574
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF574, zinc finger protein 574
  • Synonyms
    FP972
  • Links
    NCBI Gene ID: 64763
    neXtProt AC: NX_Q6ZN55
    UniProt: Q6ZN55

  • Chr Location
    19q13.2; chr19:42068477-42081552 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    736
  • Tissues
    30
  • cDNA Data
    76
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 232976 NCBI Gene Model | MGI Sequence Detail 7819 C57BL/6J ±  kb
transcript NM_001168506 RefSeq | MGI Sequence Detail 4978 C57BL/6  
polypeptide Q8BY46 UniProt | EBI | MGI Sequence Detail 900 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 76
    cDNA 76

    Microarray probesets 4
References
more
  • Summaries
    All 30
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:354285 Zhong X, et al., Disruption of the ZFP574-THAP12 complex suppresses B cell malignancies in mice. Proc Natl Acad Sci U S A. 2024 Jul 30;121(31):e2409232121
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory