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Ino80c Gene Detail
Summary
  • Symbol
    Ino80c
  • Name
    INO80 complex subunit C
  • Synonyms
    D030070L09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443014
    NCBI Gene: 225280
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:24237818-24254876 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 18, 12.74 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    550 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443014
protein coding gene Chr18:24237814-24255010 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024198
protein coding gene Chr18:21823419-21842448 (-)
A/J MGP_AJ_G0024163
protein coding gene Chr18:21233366-21251463 (-)
AKR/J MGP_AKRJ_G0024132
protein coding gene Chr18:21876152-21907523 (-)
BALB/cJ MGP_BALBcJ_G0024163
protein coding gene Chr18:21283221-21306523 (-)
C3H/HeJ MGP_C3HHeJ_G0023931
protein coding gene Chr18:21819906-21837789 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024605
protein coding gene Chr18:22762581-22780779 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022047
protein coding gene Chr18:21109931-21127095 (-)
CAST/EiJ MGP_CASTEiJ_G0023405
protein coding gene Chr18:21594887-21614633 (-)
CBA/J MGP_CBAJ_G0023899
protein coding gene Chr18:23371645-23394676 (-)
DBA/2J MGP_DBA2J_G0024031
protein coding gene Chr18:20907061-20925907 (-)
FVB/NJ MGP_FVBNJ_G0023997
protein coding gene Chr18:20666142-20683193 (-)
LP/J MGP_LPJ_G0024112
protein coding gene Chr18:21994370-22010458 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024025
protein coding gene Chr18:24386470-24408955 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024653
protein coding gene Chr18:21635291-21651801 (-)
PWK/PhJ MGP_PWKPhJ_G0023149
protein coding gene Chr18:21044512-21062464 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022958
protein coding gene Chr18:21866857-21890032 (-)
WSB/EiJ MGP_WSBEiJ_G0023469
protein coding gene Chr18:21531925-21549581 (-)



Homology
more
  • Human Ortholog
    INO80C, INO80 complex subunit C
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    INO80C, INO80 complex subunit C
  • Synonyms
    C18orf37, hIes6, IES6
  • Links
    NCBI Gene ID: 125476
    neXtProt AC: NX_Q6PI98
    UniProt: Q6PI98

  • Chr Location
    18q12.2; chr18:35452230-35497979 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Sequences &
    Gene Models
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    Representative SequencesLengthStrain/SpeciesFlank
    genomic 225280 NCBI Gene Model | MGI Sequence Detail 17059 C57BL/6J ±  kb
    transcript NM_172625 RefSeq | MGI Sequence Detail 2360 C57BL/6  
    polypeptide Q8BHA0 UniProt | EBI | MGI Sequence Detail 191 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 44
      cDNA 44

      Microarray probesets 4
    References
    more
    • Summaries
      All 30
      Gene Ontology 6
      Phenotypes 7
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    11/12/2024
    MGI 6.24
    The Jackson Laboratory