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Tnrc6c Gene Detail
Summary
  • Symbol
    Tnrc6c
  • Name
    trinucleotide repeat containing 6C
  • Synonyms
    9930033H14Rik, mKIAA1582
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443265
    NCBI Gene: 217351
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:117545115-117654265 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 82.96 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2409 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443265
 protein coding gene Chr11:117544529-117654265 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019448
 protein coding gene Chr11:121922430-122042983 (+)
A/J MGP_AJ_G0019416
 protein coding gene Chr11:116522941-116633355 (+)
AKR/J MGP_AKRJ_G0019386
 protein coding gene Chr11:120069690-120182707 (+)
BALB/cJ MGP_BALBcJ_G0019391
 protein coding gene Chr11:116894250-117005851 (+)
C3H/HeJ MGP_C3HHeJ_G0019197
 protein coding gene Chr11:120346625-120460538 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019840
 protein coding gene Chr11:125639173-125764461 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017465
 protein coding gene Chr11:113536068-113641968 (+)
CAST/EiJ MGP_CASTEiJ_G0018751
 protein coding gene Chr11:121781438-121896264 (+)
CBA/J MGP_CBAJ_G0019168
 protein coding gene Chr11:130598780-130717301 (+)
DBA/2J MGP_DBA2J_G0019280
 protein coding gene Chr11:115925299-116034064 (+)
FVB/NJ MGP_FVBNJ_G0019272
 protein coding gene Chr11:115541905-115654247 (+)
LP/J MGP_LPJ_G0019350
 protein coding gene Chr11:122250386-122367126 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019305
 protein coding gene Chr11:129570628-129685464 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019879
 protein coding gene Chr11:120714350-120829995 (+)
PWK/PhJ MGP_PWKPhJ_G0018517
 protein coding gene Chr11:117278955-117390651 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018309
 protein coding gene Chr11:120441706-120560443 (+)
WSB/EiJ MGP_WSBEiJ_G0018803
 protein coding gene Chr11:120686924-120799949 (+)



Homology
more
  • Human Ortholog
    TNRC6C, trinucleotide repeat containing adaptor 6C
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TNRC6C, trinucleotide repeat containing adaptor 6C
  • Links
    NCBI Gene ID: 57690
    neXtProt AC: NX_Q9HCJ0
    UniProt: Q9HCJ0

  • Chr Location
    17q25.3; chr17:77957557-78108835 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 2 alleles in 2 genetic backgrounds
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trap allele exhibit complete neonatal lethality with cyanosis, respiratory distress and thickened mesenchyme in air sacs.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    742
  • Tissues
    29
  • cDNA Data
    10
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025571 Ensembl Gene Model | MGI Sequence Detail 109151 C57BL/6J ±  kb
transcript ENSMUST00000106344 Ensembl | MGI Sequence Detail 8847 Not Applicable  
polypeptide ENSMUSP00000101951 Ensembl | MGI Sequence Detail 1900 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    Genomic 2
    cDNA 10
    Primer pair 3
    Other 1

    Microarray probesets 7
References
more
  • Summaries
    All 39
    Developmental Gene Expression 4
    Gene Ontology 6
    Phenotypes 12
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory