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Lancl3 Gene Detail
Summary
  • Symbol
    Lancl3
  • Name
    LanC lantibiotic synthetase component C-like 3 (bacterial)
  • Synonyms
    6030463G20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443335
    NCBI Gene: 236285
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:9066212-9134324 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 4.18 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1665 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443335
 protein coding gene ChrX:9066141-9134324 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035553
 protein coding gene ChrX:3869135-3986210 (+)
A/J MGP_AJ_G0035530
 protein coding gene ChrX:3980236-4049444 (+)
AKR/J MGP_AKRJ_G0035463
 protein coding gene ChrX:4009787-4084187 (+)
BALB/cJ MGP_BALBcJ_G0035523
 protein coding gene ChrX:3935797-4004901 (+)
C3H/HeJ MGP_C3HHeJ_G0035240
 protein coding gene ChrX:4064743-4132243 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036053
 protein coding gene ChrX:3957579-4034003 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032922
 protein coding gene ChrX:3337647-3423148 (+)
CAST/EiJ MGP_CASTEiJ_G0034532
 protein coding gene ChrX:3761605-3873199 (+)
CBA/J MGP_CBAJ_G0035209
 protein coding gene ChrX:4328252-4397522 (+)
DBA/2J MGP_DBA2J_G0035363
 protein coding gene ChrX:3949022-4017424 (+)
FVB/NJ MGP_FVBNJ_G0035310
 protein coding gene ChrX:3754144-3826359 (+)
LP/J MGP_LPJ_G0035445
 protein coding gene ChrX:4068387-4188070 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035352
 protein coding gene ChrX:4206151-4271669 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036065
 protein coding gene ChrX:3863658-3932624 (+)
PWK/PhJ MGP_PWKPhJ_G0034233
 protein coding gene ChrX:3434174-3547128 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034073
 protein coding gene ChrX:3905534-4034147 (+)
WSB/EiJ MGP_WSBEiJ_G0034669
 protein coding gene ChrX:3912945-4024168 (+)



Homology
more
  • Human Ortholog
    LANCL3, LanC like family member 3
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LANCL3, LanC like family member 3
  • Links
    NCBI Gene ID: 347404
    neXtProt AC: NX_Q6ZV70
    UniProt: Q6ZV70

  • Chr Location
    Xp21.1; chrX:37571569-37684463 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    2 phenotypes from multigenic genotypes
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    6
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 236285 NCBI Gene Model | MGI Sequence Detail 68113 C57BL/6J ±  kb
    transcript NM_173414 RefSeq | MGI Sequence Detail 3920 C57BL/6  
    polypeptide Q8CD19 UniProt | EBI | MGI Sequence Detail 420 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 6
      cDNA 6

      Microarray probesets 2
    References
    more
    • Summaries
      All 28
      Developmental Gene Expression 1
      Gene Ontology 2
      Phenotypes 8
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory